Phospholipids of APOE lipoproteins activate microglia in an isoform-specific manner in preclinical models of Alzheimer’s disease

by Nicholas F. Fitz, Kyong Nyon Nam, Cody M. Wolfe, Florent Letronne, Brittany E. Playso, Bistra E. Iordanova, Takashi D. Y. Kozai, Richard J. Biedrzycki, Valerian E. Kagan, Yulia Y. Tyurina, Xianlin Han, Iliya Lefterov, Radosveta Koldamova
Published 2021-06-01

APOE2 orchestrated differences in transcriptomic and lipidomic profiles of postmortem AD brain

by Iliya Lefterov, Cody M. Wolfe, Nicholas F. Fitz, Kyong Nyon Nam, Florent Letronne, Richard J. Biedrzycki, Julia Kofler, Xianlin Han, Jianing Wang, Jonathan Schug, Radosveta Koldamova
Published 2019-12-01

EFA6 in Axon Regeneration, as a Microtubule Regulator and as a Guanine Nucleotide Exchange Factor

by Gilberto Gonzalez, Lizhen Chen
Published 2021-05-01

ZBTB20 is required for anterior pituitary development and lactotrope specification

by Dongmei Cao, Xianhua Ma, Jiao Cai, Jing Luan, An-Jun Liu, Rui Yang, Yi Cao, Xiaotong Zhu, Hai Zhang, Yu-Xia Chen, Yuguang Shi, Guang-Xia Shi, Dajin Zou, Xuetao Cao, Michael J. Grusby, Zhifang Xie, Weiping J. Zhang
Published 2016-04-01

Adipose group 1 innate lymphoid cells promote adipose tissue fibrosis and diabetes in obesity

by Hongdong Wang, Lei Shen, Xitai Sun, Fangcen Liu, Wenhuan Feng, Chunping Jiang, Xuehui Chu, Xiao Ye, Can Jiang, Yan Wang, Pengzi Zhang, Mengwei Zang, Dalong Zhu, Yan Bi
Published 2019-07-01

The CCR4–NOT deadenylase complex safeguards thymic positive selection by down-regulating aberrant pro-apoptotic gene expression

by Taku Ito-Kureha, Takahisa Miyao, Saori Nishijima, Toru Suzuki, Shin-ichi Koizumi, Alejandro Villar-Briones, Akinori Takahashi, Nobuko Akiyama, Masahiro Morita, Isao Naguro, Hiroki Ishikawa, Hidenori Ichijo, Taishin Akiyama, Tadashi Yamamoto
Published 2020-12-01

Regulation of hepatic lipogenesis by the zinc finger protein Zbtb20

by Gan Liu, Luting Zhou, Hai Zhang, Rong Chen, Ye Zhang, Ling Li, Jun-Yu Lu, Hui Jiang, Dong Liu, Shasha Qi, Ying-Ming Jiang, Kai Yin, Zhifang Xie, Yuguang Shi, Yong Liu, Xuetao Cao, Yu-Xia Chen, Dajin Zou, Weiping J. Zhang
Published 2017-03-01

Moderate lifelong overexpression of tuberous sclerosis complex 1 (TSC1) improves health and survival in mice

by Hong-Mei Zhang, Vivian Diaz, Michael E. Walsh, Yiqiang Zhang
Published 2017-04-01

Axon Injury-Induced Autophagy Activation Is Impaired in a <i>C. elegans</i> Model of Tauopathy

by Su-Hyuk Ko, Gilberto Gonzalez, Zhijie Liu, Lizhen Chen
Published 2020-11-01

Patient-specific induced pluripotent stem cells in neurological disease modeling: the importance of nonhuman primate models

by Qiu Z, Farnsworth SL, Mishra A, Hornsby PJ
Published 2013-07-01

Organization of the Mammalian Ionome According to Organ Origin, Lineage Specialization, and Longevity

by Siming Ma, Sang-Goo Lee, Eun Bae Kim, Thomas J. Park, Andrei Seluanov, Vera Gorbunova, Rochelle Buffenstein, Javier Seravalli, Vadim N. Gladyshev
Published 2015-11-01

Dynamic Interactions of Transcription Factors and Enhancer Reprogramming in Cancer Progression

by Emily Zboril, Hannah Yoo, Lizhen Chen, Lizhen Chen, Zhijie Liu
Published 2021-09-01

Beta-guanidinopropionic acid does not extend Drosophila lifespan

by Jonathan D. Dorigatti, Kevin M. Thyne, Brett C. Ginsburg, Adam B. Salmon
Published 2021-09-01

Lipidomics Revealed Aberrant Metabolism of Lipids Including FAHFAs in Renal Tissue in the Progression of Lupus Nephritis in a Murine Model

by Changfeng Hu, Yu Du, Xiaofen Xu, Haichang Li, Qiao Duan, Zhijun Xie, Chengping Wen, Xianlin Han
Published 2021-02-01

Exercise preserves muscle mass and force in a prostate cancer mouse model

by Darpan I. Patel, Kira Abuchowski, Bilal Sheikh, Paul Rivas, Nicolas Musi, A. Pratap Kumar
Published 2019-11-01

Overcoming barriers to reprogramming and differentiation in nonhuman primate induced pluripotent stem cells

by J. J. Hemmi, A. Mishra, P. J. Hornsby
Published 2017-08-01

Bone Mineral Density Changes during Weight Regain following Weight Loss with and without Exercise

by Monica C. Serra, Alice S. Ryan
Published 2021-08-01

APOE2 is associated with longevity independent of Alzheimer’s disease

by Mitsuru Shinohara, Takahisa Kanekiyo, Masaya Tachibana, Aishe Kurti, Motoko Shinohara, Yuan Fu, Jing Zhao, Xianlin Han, Patrick M Sullivan, G William Rebeck, John D Fryer, Michael G Heckman, Guojun Bu
Published 2020-10-01

Nexrutine® preserves muscle mass similar to exercise in prostate cancer mouse model

by Darpan I. Patel, Derek Wallace, Kira Abuchowski, Paul Rivas, Amber Gallegos, Nicolas Musi, Addanki Pratap. Kumar
Published 2019-08-01

Effect of oxygen tension on bioenergetics and proteostasis in young and old myoblast precursor cells

by M. Konigsberg, V.I. Pérez, C. Ríos, Y. Liu, S. Lee, Y. Shi, H. Van Remmen
Published 2013-01-01