Pharmacokinetic study of seven bioactive components of Xiaoyan Lidan Formula in cholestatic and control rats using UPLC-MS/MS

by Kaihui Zhang, Meiqi Wang, Yufeng Yao, Tao Huang, Fangle Liu, Chenchen Zhu, Chaozhan Lin
Published 2021-07-01

Pyrazole ring-containing isolongifolanone derivatives as potential CDK2 inhibitors: Evaluation of anticancer activity and investigation of action mechanism

by Yunyun Wang, Wei Shi, Chenliang Wu, Lin Wan, Yuxun Zhao, Chenglong Zhang, Wen Gu, Shifa Wang
Published 2021-07-01

Pinus kesiya Royle ex Gordon induces apoptotic cell death in hepatocellular carcinoma HepG2 cell via intrinsic pathway by PARP and Topoisomerase I suppression

by Piman Pocasap, Apiyada Nonpunya, Natthida Weerapreeyakul
Published 2021-07-01

Metformin and insulin-resistant related diseases: Emphasis on the role of microRNAs

by Nahid Alimoradi, Negar Firouzabadi, Reihaneh Fatehi
Published 2021-07-01

Small molecules against the origin and activation of myofibroblast for renal interstitial fibrosis therapy

by Ya-long Feng, Wen-bo Wang, Yue Ning, Hua Chen, Pei Liu
Published 2021-07-01

Potential medicinal value of celastrol and its synthesized analogues for central nervous system diseases

by Xue Bai, Rui-Jia Fu, Shuo Zhang, Shi-Jun Yue, Yan-Yan Chen, Ding-Qiao Xu, Yu-Ping Tang
Published 2021-07-01

Mirogabalin, a novel ligand for α2δ subunit of voltage-gated calcium channels, improves cognitive impairments in repeated intramuscular acidic saline injection model rats, an exper...

by Hiroyasu Murasawa, Akiko Pawlak, Hiroyuki Kobayashi, Kensuke Saeki, Shun-ichi Yasuda, Yutaka Kitano
Published 2021-07-01

NF-KappaB interacting LncRNA: Review of its roles in neoplastic and non-neoplastic conditions

by Bashdar Mahmud Hussen, Tahereh Azimi, Hazha Jamal Hidayat, Mohammad Taheri, Soudeh Ghafouri-Fard
Published 2021-07-01

Editorial Board

Published 2021-07-01

A fungus-derived purpactin A as an inhibitor of TMEM16A chloride channels and mucin secretion in airway epithelial cells

by Chantapol Yimnual, Saravut Satitsri, Baiq Nila Sari Ningsih, Vatcharin Rukachaisirikul, Chatchai Muanprasat
Published 2021-07-01

Coronary hypercontractility to acidosis owes to the greater activity of TMEM16A/ANO1 in the arterial smooth muscle cells

by Pengmei Guo, Yu Liu, Xiaojia Xu, Guijin Ma, Xiaomin Hou, Yanying Fan, Mingsheng Zhang
Published 2021-07-01

Novel and emerging mutations of SARS-CoV-2: Biomedical implications

by Elmira Mohammadi, Fatemeh Shafiee, Kiana Shahzamani, Mohammad Mehdi Ranjbar, Abbas Alibakhshi, Shahrzad Ahangarzadeh, Leila Beikmohammadi, Laleh Shariati, Soodeh Hooshmandi, Behrooz Ataei, Shaghayegh Haghjooy Javanmard
Published 2021-07-01

Hyper-activated platelet lysates prevent glucocorticoid-associated femoral head necrosis by regulating autophagy

by Zhipeng Huang, Qinglong Wang, Tao Zhang, Yinsheng Fu, Wenbo Wang
Published 2021-07-01

Potential anti-inflammatory effect of erythropoietin in non-clinical studies in vivo: A systematic review

by Inês Silva, Carolina Alípio, Rui Pinto, Vanessa Mateus
Published 2021-07-01

Role of microbiota-derived short-chain fatty acids in nervous system disorders

by Rasoul Mirzaei, Behnaz Bouzari, Seyed Reza Hosseini-Fard, Maryam Mazaheri, Yaghoub Ahmadyousefi, Milad Abdi, Saba Jalalifar, Zahra Karimitabar, Ali Teimoori, Hossein Keyvani, Farhad Zamani, Rasoul Yousefimashouf, Sajad Karampoor
Published 2021-07-01

Host immune response against leishmaniasis and parasite persistence strategies: A review and assessment of recent research

by Ehab Kotb Elmahallawy, Abdulsalam A.M. Alkhaldi, Amira A. Saleh
Published 2021-07-01

Exercise and Urtica dioica extract ameliorate hippocampal insulin signaling, oxidative stress, neuroinflammation, and cognitive function in STZ-induced diabetic rats

by Masoud Rahmati, Maryam Keshvari, Rahim Mirnasouri, Farzaneh Chehelcheraghi
Published 2021-07-01

Advances in developing therapeutic strategies for Alzheimer's disease

by Thuy Trang Nguyen, Thi Thuy Dung Nguyen, Thi Kim Oanh Nguyen, Tuong Kha Vo, Van Giau Vo
Published 2021-07-01

Can Src protein tyrosine kinase inhibitors be combined with opioid analgesics? Src and opioid-induced tolerance, hyperalgesia and addiction

by Yaoyuan Li, Yanju Bao, Honggang Zheng, Yinggang Qin, Baojin Hua
Published 2021-07-01

Preclinical tolerance evaluation of the addition of a cisplatin-based dry powder for inhalation to the conventional carboplatin-paclitaxel doublet for treatment of non-small cell l...

by S. Chraibi, R. Rosière, E. De Prez, P. Gérard, MH. Antoine, I. Langer, J. Nortier, M. Remmelink, K. Amighi, N. Wauthoz
Published 2021-07-01