Ginsenoside Compound K Attenuates Ox-LDL-Mediated Macrophage Inflammation and Foam Cell Formation via Autophagy Induction and Modulating NF-κB, p38, and JNK MAPK Signaling

by Shan Lu, Shan Lu, Shan Lu, Shan Lu, Shan Lu, Yun Luo, Yun Luo, Yun Luo, Yun Luo, Yun Luo, GuiBo Sun, GuiBo Sun, GuiBo Sun, GuiBo Sun, GuiBo Sun, XiaoBo Sun, XiaoBo Sun, XiaoBo Sun, XiaoBo Sun, XiaoBo Sun
Published 2020-09-01

Promotion of compound K production in Saccharomyces cerevisiae by glycerol

by Weihua Nan, Fanglong Zhao, Chuanbo Zhang, Haiyan Ju, Wenyu Lu
Published 2020-02-01

General and Genetic Toxicology of Enzyme-Treated Ginseng Extract Toxicology of Ginseng Rh2+

by Mi-Kyung Jeong, Chong-Kwan Cho, Hwa-Seung Yoo
Published 2016-09-01

Nuclear factor kappa-B- and activator protein-1-mediated immunostimulatory activity of compound K in monocytes and macrophages

by Woo Seok Yang, Young-Su Yi, Donghyun Kim, Min Ho Kim, Jae Gwang Park, Eunji Kim, Sang Yeol Lee, Keejung Yoon, Jong-Hoon Kim, Junseong Park, Jae Youl Cho
Published 2017-07-01

Polymorphic Characterization, Pharmacokinetics, and Anti-Inflammatory Activity of Ginsenoside Compound K Polymorphs

by Yun-Yan Kuang, Xuan Gao, Yi-Jun Niu, Xun-Long Shi, Wei Zhou
Published 2021-04-01

Enzymatically Synthesized Ginsenoside Exhibits Antiproliferative Activity in Various Cancer Cell Lines

by Sumangala Darsandhari, Biplav Shrestha, Ramesh Prasad Pandey, Sanghun Lee, Hye Jin Jung, Yeon Ju Kim, Jae Kyung Sohng
Published 2019-03-01

A prebiotic fiber increases the formation and subsequent absorption of compound K following oral administration of ginseng in rats

by Kyung-Ah Kim, Hye Hyun Yoo, Wan Gu, Dae-Hyung Yu, Ming Ji Jin, Hae-Lim Choi, Kathy Yuan, Laetitia Guerin-Deremaux, Dong-Hyun Kim
Published 2015-04-01

Compound K improves skin barrier function by increasing SPINK5 expression

by No-June Park, Sim-Kyu Bong, Sullim Lee, Yujung Jung, Hyun Jegal, Jinchul Kim, Si-Kwan Kim, Yong Kee Kim, Su-Nam Kim
Published 2020-11-01

Pharmacokinetics and Intestinal Metabolism of Compound K in Rats and Mice

by Ji-Hyeon Jeon, Bitna Kang, Sowon Lee, Sojeong Jin, Min-Koo Choi, Im-Sook Song
Published 2020-02-01

Compound K Attenuates the Development of Atherosclerosis in ApoE−/− Mice via LXRα Activation

by Li Zhou, Yu Zheng, Zhuoying Li, Lingxia Bao, Yin Dou, Yuan Tang, Jianxiang Zhang, Jianzhi Zhou, Ya Liu, Yi Jia, Xiaohui Li
Published 2016-07-01

Single- and Multiple-Dose Trials to Determine the Pharmacokinetics, Safety, Tolerability, and Sex Effect of Oral Ginsenoside Compound K in Healthy Chinese Volunteers

by Lulu Chen, Lulu Chen, Luping Zhou, Luping Zhou, Jie Huang, Yaqin Wang, Yaqin Wang, Guoping Yang, Zhirong Tan, Zhirong Tan, Yicheng Wang, Yicheng Wang, Gan Zhou, Gan Zhou, Jianwei Liao, Jianwei Liao, Dongsheng Ouyang, Dongsheng Ouyang, Dongsheng Ouyang
Published 2018-01-01

Enzymatic formation of compound-K from ginsenoside Rb1 by enzyme preparation from cultured mycelia of Armillaria mellea

by Jitendra Upadhyaya, Min-Ji Kim, Young-Hoi Kim, Sung-Ryong Ko, Hee-Won Park, Myung-Kon Kim
Published 2016-04-01

Highly Selective Bioconversion of Ginsenoside Rb1 to Compound K by the Mycelium of Cordyceps sinensis under Optimized Conditions

by Wei-Nan Wang, Bing-Xiong Yan, Wen-Di Xu, Ye Qiu, Yun-Long Guo, Zhi-Dong Qiu
Published 2015-10-01

Amelioration of dry eye syndrome by oral administration of cultivated wild ginseng extract

by Jae Sung Pyo, Hyung Hoi Kim, Kang Min Kim, Jae Seon Kang
Published 2019-04-01

The ginsenoside metabolite compound K inhibits hormone-independent breast cancer through downregulation of cyclin D1

by Seung Joon Lee, Ji Su Lee, Eunjung Lee, Tae-Gyu Lim, Sanguine Byun
Published 2018-07-01

Ginsenoside Compound K Regulates HIF-1α-Mediated Glycolysis Through Bclaf1 to Inhibit the Proliferation of Human Liver Cancer Cells

by Silin Zhang, Meilan Zhang, Jiaxin Chen, Jiaqi Zhao, Jielin Su, Xuewu Zhang
Published 2020-12-01

Bioconversion of ginsenoside Rb1 into compound K by Leuconostoc citreum LH1 isolated from kimchi

by Lin-Hu Quan, Jin-Ying Piao, Jin-Woo Min, Dong-Uk Yang, Hee Nyeong Lee, Deok Chun Yang
Published 2011-09-01

Determination of ginsenoside compound K in human plasma by liquid chromatography–tandem mass spectrometry of lithium adducts

by Yunhui Chen, Youming Lu, Yong Yang, Xiaoyan Chen, Liang Zhu, Dafang Zhong
Published 2015-09-01

Improved conversion of ginsenoside Rb1 to compound K by semi-rational design of Sulfolobus solfataricus β-glycosidase

by Kyung-Chul Shin, Hye-Yeon Choi, Min-Ju Seo, Deok-Kun Oh
Published 2017-10-01

Synthesis and Biological Evaluation of Ginsenoside Compound K Derivatives as a Novel Class of LXRα Activator

by Yan Huang, Hongmei Liu, Yingxian Zhang, Jin Li, Chenping Wang, Li Zhou, Yi Jia, Xiaohui Li
Published 2017-07-01