Survival among patients with relapsed/refractory diffuse large B cell lymphoma treated with single-agent selinexor in the SADAL study

by Marie Maerevoet, Josee M. Zijlstra, George Follows, Rene-Olivier Casasnovas, J. S. P. Vermaat, Nagesh Kalakonda, Andre Goy, Sylvain Choquet, Eric Van Den Neste, Brian Hill, Catherine Thieblemont, Federica Cavallo, Fatima De la Cruz, John Kuruvilla, Nada Hamad, Ulrich Jaeger, Paolo Caimi, Ronit Gurion, Krzysztof Warzocha, Sameer Bakhshi, Juan-Manuel Sancho, Michael Schuster, Miklos Egyed, Fritz Offner, Theodoros P. Vassilakopoulos, Priyanka Samal, Matthew Ku, Xiwen Ma, Kelly Corona, Kamal Chamoun, Jatin Shah, Sharon Shacham, Michael G. Kauffman, Miguel Canales
Published 2021-07-01

Effect of prior treatments on selinexor, bortezomib, and dexamethasone in previously treated multiple myeloma

by Maria V. Mateos, Maria Gavriatopoulou, Thierry Facon, Holger W. Auner, Xavier Leleu, Roman Hájek, Meletios A. Dimopoulos, Sosana Delimpasi, Maryana Simonova, Ivan Špička, Ludĕk Pour, Iryna Kriachok, Halyna Pylypenko, Vadim Doronin, Ganna Usenko, Reuben Benjamin, Tuphan K. Dolai, Dinesh K. Sinha, Christopher P. Venner, Mamta Garg, Don A. Stevens, Hang Quach, Sundar Jagannath, Philippe Moreau, Moshe Levy, Ashraf Z. Badros, Larry D. Anderson, Nizar J. Bahlis, Michele Cavo, Yi Chai, Jacqueline Jeha, Melina Arazy, Jatin Shah, Sharon Shacham, Michael G. Kauffman, Paul G. Richardson, Sebastian Grosicki
Published 2021-04-01

Structural determinants of nuclear export signal orientation in binding to exportin CRM1

by Ho Yee Joyce Fung, Szu-Chin Fu, Chad A Brautigam, Yuh Min Chook
Published 2015-09-01

New insights into YAP/TAZ nucleo‐cytoplasmic shuttling: new cancer therapeutic opportunities?

by Michal Shreberk‐Shaked, Moshe Oren
Published 2019-06-01

Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals

by Ho Yee Joyce Fung, Szu-Chin Fu, Yuh Min Chook
Published 2017-03-01

XPO1 inhibition with selinexor synergizes with proteasome inhibition in neuroblastoma by targeting nuclear export of IkB

by Basia Galinski, Marcus Luxemburg, Yosef Landesman, Bruce Pawel, Katherine J. Johnson, Stephen R. Master, Kevin W. Freeman, David M. Loeb, Jean M. Hébert, Daniel A. Weiser
Published 2021-08-01

Effects of cadmium on osteoblast cell line: Exportin 1 accumulation, p-JNK activation, DNA damage and cell apoptosis

by Ling Ou, Haixia Wang, Zhidi Wu, Panpan Wang, Li Yang, Xiaoyun Li, Kehuan Sun, Xiaofeng Zhu, Ronghua Zhang
Published 2021-01-01

Structural Basis of Targeting the Exportin CRM1 in Cancer

by Achim Dickmanns, Thomas Monecke, Ralf Ficner
Published 2015-09-01

Novel therapies for treatment of Ph+ acute leukemias

by Walker, Christopher James
Published 2013

Exportin-1-Dependent Nuclear Export of DEAD-box Helicase DDX3X is Central to its Role in Antiviral Immunity

by Steven M. Heaton, Sarah C. Atkinson, Melissa N. Sweeney, Sundy N. Y. Yang, David A. Jans, Natalie A. Borg
Published 2019-09-01

Translocation Biosensors – Cellular System Integrators to Dissect CRM1-Dependent Nuclear Export by Chemicogenomics

by Roland H. Stauber, Shirley K. Knauer, Jens Peter von Kries, Carolin Bier, Verena Fetz
Published 2009-07-01

Human Exportin-1 is a Target for Combined Therapy of HIV and AIDS Related Lymphoma

by Eline Boons, Els Vanstreels, Maarten Jacquemyn, Tatiane C. Nogueira, Jasper E. Neggers, Thomas Vercruysse, Joost van den Oord, Sharon Tamir, Sharon Shacham, Yosef Landesman, Robert Snoeck, Christophe Pannecouque, Graciela Andrei, Dirk Daelemans
Published 2015-09-01

A Curious Novel Combination of <i>Nucleophosmin</i> (<i>NPM1</i>) Gene Mutations Leading to Aberrant Cytoplasmic Dislocation of <i>NPM1</i> in Acute Myeloid Leukemia (AML)

by Alessandra Venanzi, Roberta Rossi, Giovanni Martino, Ombretta Annibali, Giuseppe Avvisati, Maria Grazia Mameli, Paolo Sportoletti, Enrico Tiacci, Brunangelo Falini, Maria Paola Martelli
Published 2021-09-01

Nuclear Export Inhibition for Pancreatic Cancer Therapy

by Irfana Muqbil, Asfar S. Azmi, Ramzi M. Mohammad
Published 2018-05-01