human 214 male 151 Article 150 Humans 148 female 147 controlled study 127 adult 124 article 99 gene frequency 94 Female 91 Male 90 major clinical study 59 Adult 55 genetics 54 middle aged 54 human experiment 47 single nucleotide polymorphism 47 Frequency domain analysis 46 Middle Aged 46 Natural frequencies 44 genotype 43 nonhuman 39 physiology 39 aged 38 young adult 37 clinical article 33 High frequency HF 32 Young Adult 32 genetic association 31 Frequency response 30