A Neurotoxic Ménage-à-trois: Glutamate, Calcium, and Zinc in the Excitotoxic Cascade

by Alberto Granzotto, Alberto Granzotto, Alberto Granzotto, Lorella M. T. Canzoniero, Stefano L. Sensi, Stefano L. Sensi, Stefano L. Sensi
Published 2020-11-01

Modulation of β-Amyloid Fibril Formation in Alzheimer’s Disease by Microglia and Infection

by Madeleine R. Brown, Sheena E. Radford, Eric W. Hewitt
Published 2020-11-01

MIRRAGGE – Minimum Information Required for Reproducible AGGregation Experiments

by Pedro M. Martins, Pedro M. Martins, Susanna Navarro, Alexandra Silva, Maria F. Pinto, Zsuzsa Sárkány, Francisco Figueiredo, Francisco Figueiredo, Francisco Figueiredo, Pedro José Barbosa Pereira, Francisca Pinheiro, Zuzana Bednarikova, Michał Burdukiewicz, Oxana V. Galzitskaya, Oxana V. Galzitskaya, Zuzana Gazova, Cláudio M. Gomes, Annalisa Pastore, Louise C. Serpell, Rostislav Skrabana, Rostislav Skrabana, Vytautas Smirnovas, Mantas Ziaunys, Daniel E. Otzen, Salvador Ventura, Sandra Macedo-Ribeiro
Published 2020-11-01

The Neuromuscular Junction in Health and Disease: Molecular Mechanisms Governing Synaptic Formation and Homeostasis

by Pedro M. Rodríguez Cruz, Pedro M. Rodríguez Cruz, Judith Cossins, Judith Cossins, David Beeson, David Beeson, Angela Vincent, Angela Vincent
Published 2020-12-01

Gene Therapy Vector Encoding Neuropeptide Y and Its Receptor Y2 for Future Treatment of Epilepsy: Preclinical Data in Rats

by Julia Alicja Szczygieł, Kira Iben Danielsen, Kira Iben Danielsen, Esbjörn Melin, Søren Hofman Rosenkranz, Stanislava Pankratova, Annika Ericsson, Karin Agerman, Merab Kokaia, David Paul Drucker Woldbye
Published 2020-12-01

Hypoxia-Ischemia Induced Age-Dependent Gene Transcription Effects at Two Development Stages in the Neonate Mouse Brain

by Nicolas Dupré, Céline Derambure, Bérénice Le Dieu-Lugon, Michelle Hauchecorne, Yannick Detroussel, Bruno J. Gonzalez, Stéphane Marret, Stéphane Marret, Philippe Leroux
Published 2020-12-01

New Insights Into Drug Discovery Targeting Tau Protein

by Yoshiyuki Soeda, Akihiko Takashima
Published 2020-12-01

Neurogenetic and Neuroepigenetic Mechanisms in Cognitive Health and Disease

by Davide Martino Coda, Johannes Gräff
Published 2020-12-01

Neuroinflammation-Induced Upregulation of Glial Cathepsin X Expression and Activity in vivo

by Anja Pišlar, Larisa Tratnjek, Larisa Tratnjek, Gordana Glavan, Nace Zidar, Marko Živin, Janko Kos, Janko Kos
Published 2020-11-01

Cell Adhesion Molecules and Protein Synthesis Regulation in Neurons

by Irina Kozlova, Saroj Sah, Ryan Keable, Iryna Leshchyns’ka, Michael Janitz, Vladimir Sytnyk
Published 2020-11-01

L-Asparaginase Exerts Neuroprotective Effects in an SH-SY5Y-A53T Model of Parkinson’s Disease by Regulating Glutamine Metabolism

by Qingxi Zhang, Qingxi Zhang, Yuyuan Gao, Jiahui Zhang, You Li, Jianing Chen, Rui Huang, Guixian Ma, Limin Wang, Yuhu Zhang, Kun Nie, Kun Nie, Lijuan Wang, Lijuan Wang
Published 2020-09-01

Neuronal Activity at Synapse Resolution: Reporters and Effectors for Synaptic Neuroscience

by Francesco Gobbo, Francesco Gobbo, Antonino Cattaneo
Published 2020-10-01

P2X7 Receptor-Dependent Layer-Specific Changes in Neuron-Microglia Reactivity in the Prefrontal Cortex of a Phencyclidine Induced Mouse Model of Schizophrenia

by Stefano Calovi, Stefano Calovi, Paula Mut-Arbona, Paula Mut-Arbona, Pál Tod, András Iring, Annette Nicke, Susana Mato, Susana Mato, Susana Mato, Susana Mato, E. Sylvester Vizi, Jan Tønnesen, Jan Tønnesen, Beata Sperlagh
Published 2020-11-01

Functional Interactions of Tau Phosphorylation Sites That Mediate Toxicity and Deficient Learning in Drosophila melanogaster

by Iason Keramidis, Ergina Vourkou, Ergina Vourkou, Katerina Papanikolopoulou, Efthimios M. C. Skoulakis
Published 2020-10-01

Kinase Domain Is a Dynamic Hub for Driving LRRK2 Allostery

by Susan S. Taylor, Susan S. Taylor, Pallavi Kaila-Sharma, Jui-Hung Weng, Phillip Aoto, Sven H. Schmidt, Stefan Knapp, Stefan Knapp, Sebastian Mathea, Sebastian Mathea, Friedrich W. Herberg
Published 2020-10-01

Dystroglycan Mediates Clustering of Essential GABAergic Components in Cerebellar Purkinje Cells

by Federica Briatore, Giulia Pregno, Silvia Di Angelantonio, Silvia Di Angelantonio, Elena Frola, Maria Egle De Stefano, Cyrille Vaillend, Marco Sassoè-Pognetto, Annarita Patrizi, Annarita Patrizi
Published 2020-08-01

Quantitative Changes in the Mitochondrial Proteome of Cerebellar Synaptosomes From Preclinical Cystatin B-Deficient Mice

by Katarin Gorski, Katarin Gorski, Albert Spoljaric, Tuula A. Nyman, Kai Kaila, Brendan J. Battersby, Anna-Elina Lehesjoki, Anna-Elina Lehesjoki
Published 2020-11-01

Enhanced Prefrontal Neuronal Activity and Social Dominance Behavior in Postnatal Forebrain Excitatory Neuron-Specific Cyfip2 Knock-Out Mice

by Yinhua Zhang, Yinhua Zhang, Rim Kang Hyae, Rim Kang Hyae, Seung-Hyun Lee, Yoonhee Kim, Ruiying Ma, Ruiying Ma, Chunmei Jin, Chunmei Jin, Ji-Eun Lim, Seoyeon Kim, Yeju Kang, Hyojin Kang, Su Yeon Kim, Su Yeon Kim, Seok-Kyu Kwon, Se-Young Choi, Kihoon Han, Kihoon Han
Published 2020-10-01

Loss of DEK Expression Induces Alzheimer’s Disease Phenotypes in Differentiated SH-SY5Y Cells

by Allie N. Greene, Lois G. Parks, Matia B. Solomon, Matia B. Solomon, Lisa M. Privette Vinnedge, Lisa M. Privette Vinnedge
Published 2020-11-01

Effects of GABAA Receptor α3 Subunit Epilepsy Mutations on Inhibitory Synaptic Signaling

by Parnayan Syed, Nela Durisic, Robert J. Harvey, Robert J. Harvey, Pankaj Sah, Pankaj Sah, Joseph W. Lynch
Published 2020-11-01