Epigenetic regulators of neuronal ferroptosis identify novel therapeutics for neurological diseases: HDACs, transglutaminases, and HIF prolyl hydroxylases

by Orjon Rroji, Amit Kumar, Saravanan S. Karuppagounder, Rajiv R. Ratan
Published 2021-01-01

Hypoxic and pharmacological activation of HIF inhibits SARS-CoV-2 infection of lung epithelial cells

by Peter A.C. Wing, Thomas P. Keeley, Xiaodong Zhuang, Jeffrey Y. Lee, Maria Prange-Barczynska, Senko Tsukuda, Sophie B. Morgan, Adam C. Harding, Isobel L.A. Argles, Samvid Kurlekar, Marko Noerenberg, Craig P. Thompson, Kuan-Ying A. Huang, Peter Balfe, Koichi Watashi, Alfredo Castello, Timothy S.C. Hinks, William James, Peter J. Ratcliffe, Ilan Davis, Emma J. Hodson, Tammie Bishop, Jane A. McKeating
Published 2021-04-01

Anemia in Chronic Kidney Disease: From Pathophysiology and Current Treatments, to Future Agents

by Jose Portolés, Jose Portolés, Leyre Martín, Leyre Martín, José Jesús Broseta, Aleix Cases, Aleix Cases
Published 2021-03-01

Neuroprotective Effect of HIF Prolyl Hydroxylase Inhibition in an In Vitro Hypoxia Model

by Maria Savyuk, Mikhail Krivonosov, Tatiana Mishchenko, Irina Gazaryan, Mikhail Ivanchenko, Anna Khristichenko, Andrey Poloznikov, Dmitry Hushpulian, Sergey Nikulin, Evgeny Tonevitsky, Guzal Abuzarova, Elena Mitroshina, Maria Vedunova
Published 2020-07-01

Induction of erythropoiesis by hypoxia-inducible factor prolyl hydroxylase inhibitors without promotion of tumor initiation, progression, or metastasis in a VEGF-sensitive model o...

by Seeley TW, Sternlicht MD, Klaus SJ, Neff TB, Liu DY
Published 2017-03-01

Network activity in primary hippocampal cultures upon HIF-prolyl hydroxylase inhibition

by Savyuk, Maria Olegovna, Krivonosov, Mikhail Igorevich, Ivanchenko, Mihail Vasilevich, Poloznikov, A. A., Mitroshina, E. V., Vedunova, M. V.
Published 2021-05-01

LRP5 Regulates HIF-1α Stability via Interaction with PHD2 in Ischemic Myocardium

by Sujin Ju, Leejin Lim, Kwanhwan Wi, Changwon Park, Young-Jae Ki, Dong-Hyun Choi, Heesang Song
Published 2021-06-01

Protein Hydroxylation by Hypoxia-Inducible Factor (HIF) Hydroxylases: Unique or Ubiquitous?

by Moritz J. Strowitzki, Eoin P. Cummins, Cormac T. Taylor
Published 2019-04-01