human 72 Article 57 Humans 56 metabolism 51 nonhuman 42 controlled study 41 homeostasis 41 Animals 37 animal 36 male 28 mouse 25 genetics 23 Homeostasis 22 female 22 Mice 20 adult 20 oxidative stress 20 physiology 20 animal experiment 17 gene expression 17 insulin 17 obesity 16 unclassified drug 16 insulin resistance 15 animal model 14 inflammation 14 signal transduction 14 Insulin 13 Male 13 glucose 13