5 hydroxymethylcytosine 1 5 methylcytosine 1 5-Methylcytosine 1 Active DNA demethylation 1 Article 1 DNA Methylation 1 DNA demethylation 1 DNA methylation 1 DNA methylation reprogramming 1 Embryo, Mammalian 1 Human preimplantation development 1 Humans 1 Successful human embryogenesis 1 cell cycle parameters 1 congenital malformation 1 embryo 1 embryo development 1 epigenetics 1 female 1 genetics 1 human 1 mammalian embryo 1 metabolism 1 methylome 1 mouse 1 nonhuman 1 preimplantation embryo 1 pronucleus 1 time lapse imaging 1 zygote 1