Demonstrating a reduced capacity for removal of fluid from cerebral white matter and hypoxia in areas of white matter hyperintensity associated with age and dementia

by Matthew MacGregor Sharp, Satoshi Saito, Abby Keable, Maureen Gatherer, Roxana Aldea, Nivedita Agarwal, Julie E. Simpson, Stephen B. Wharton, Roy O. Weller, Roxana O. Carare
Published 2020-08-01

Cerebral amyloid angiopathy aggravates perivascular clearance impairment in an Alzheimer’s disease mouse model

by Shin Heun Kim, Ji Hoon Ahn, Hyunwoo Yang, Peter Lee, Gou Young Koh, Yong Jeong
Published 2020-11-01

Cerebral Vessels: An Overview of Anatomy, Physiology, and Role in the Drainage of Fluids and Solutes

by Nivedita Agarwal, Nivedita Agarwal, Nivedita Agarwal, Roxana Octavia Carare
Published 2021-01-01

Arterial Pulsations cannot Drive Intramural Periarterial Drainage: Significance for Aβ Drainage

by Alexandra K. Diem, Matthew MacGregor Sharp, Maureen Gatherer, Neil W. Bressloff, Roxana O. Carare, Giles Richardson
Published 2017-08-01

Vascular α1A Adrenergic Receptors as a Potential Therapeutic Target for IPAD in Alzheimer’s Disease

by Miles Frost, Abby Keable, Dan Baseley, Amber Sealy, Diana Andreea Zbarcea, Maureen Gatherer, Ho Ming Yuen, Matt MacGregor Sharp, Roy O. Weller, Johannes Attems, Colin Smith, Paul R. Chiarot, Roxana O. Carare
Published 2020-09-01

Apolipoprotein E and clusterin inhibit the early phase of amyloid-β aggregation in an in vitro model of cerebral amyloid angiopathy

by Yoshinori Endo, Kazuhiro Hasegawa, Ryo Nomura, Hidetaka Arishima, Ken-ichiro Kikuta, Taro Yamashita, Yasuteru Inoue, Mitsuharu Ueda, Yukio Ando, Mark R. Wilson, Tadanori Hamano, Yasunari Nakamoto, Hironobu Naiki
Published 2019-01-01