Diethyl Blechnic, a Novel Natural Product Isolated from Salvia miltiorrhiza Bunge, Inhibits Doxorubicin-Induced Apoptosis by Inhibiting ROS and Activating JNK1/2

by Jie Yu, Hongwei Gao, Chuanhong Wu, Qiong-Ming Xu, Jin-Jian Lu, Xiuping Chen
Published 2018-06-01

Efficacy and Mechanism of Action of Marine Alkaloid 3,10-Dibromofascaplysin in Drug-Resistant Prostate Cancer Cells

by Sergey A. Dyshlovoy, Moritz Kaune, Jessica Hauschild, Malte Kriegs, Konstantin Hoffer, Tobias Busenbender, Polina A. Smirnova, Maxim E. Zhidkov, Ekaterina V. Poverennaya, Su Jung Oh-Hohenhorst, Pavel V. Spirin, Vladimir S. Prassolov, Derya Tilki, Carsten Bokemeyer, Markus Graefen, Gunhild von Amsberg
Published 2020-12-01

IL-33-Induced Transcriptional Activation of LPIN1 Accelerates Breast Tumorigenesis

by Jin-Young Kim, Garam Kim, Sung-Chul Lim, Hong-Seok Choi
Published 2021-04-01

Combined Blockade of Smad3 and JNK Pathways Ameliorates Progressive Fibrosis in Folic Acid Nephropathy

by Mengjie Jiang, Mengjie Jiang, Jinjin Fan, Jinjin Fan, Xinli Qu, Songhui Li, Songhui Li, Susan K. Nilsson, Susan K. Nilsson, Yu Bo Yang Sun, Yaping Chen, Di Yu, Dan Liu, Bi-Cheng Liu, Mingliang Tang, Wei Chen, Wei Chen, Yi Ren, David J. Nikolic-Paterson, Xiaoyun Jiang, Jinhua Li, Jinhua Li, Jinhua Li, Xueqing Yu, Xueqing Yu, Xueqing Yu
Published 2019-08-01

Inhibition of Cartilage Acidic Protein 1 Reduces Ultraviolet B Irradiation Induced-Apoptosis through P38 Mitogen-Activated Protein Kinase and Jun Amino-Terminal Kinase Pathways

by Yinghong Ji, Xianfang Rong, Dan Li, Lei Cai, Jun Rao, Yi Lu
Published 2016-11-01

Suppression of Human Platelet Activation via Integrin α_IIbβ₃ Outside-In Independent Signal and Reduction of the Mortality in Pulmonary Thrombosis by Auraptene...

by Chih-Wei Hsia, Cheng-Lin Tsai, Joen-Rong Sheu, Wan-Jung Lu, Chih-Hsuan Hsia, Marappan Velusamy, Thanasekaran Jayakumar, Jiun-Yi Li
Published 2019-11-01

Induction Apoptosis of Erinacine A in Human Colorectal Cancer Cells Involving the Expression of TNFR, Fas, and Fas Ligand via the JNK/p300/p50 Signaling Pathway With Histone Acetyl...

by Ko-Chao Lee, Ko-Chao Lee, Kam-Fai Lee, Shui-Yi Tung, Shui-Yi Tung, Wen-Shih Huang, Wen-Shih Huang, Li-Ya Lee, Wan-Ping Chen, Chin-Chu Chen, Chih-Chuan Teng, Chih-Chuan Teng, Chien-Heng Shen, Chien-Heng Shen, Meng-Chiao Hsieh, Meng-Chiao Hsieh, Hsing-Chun Kuo, Hsing-Chun Kuo, Hsing-Chun Kuo, Hsing-Chun Kuo
Published 2019-10-01

Antiproliferative Activity of Hinokitiol, a Tropolone Derivative, Is Mediated via the Inductions of p-JNK and p-PLCγ1 Signaling in PDGF-BB-Stimulated Vascular Smooth Muscle Cells

by Po-Sheng Yang, Meng-Jiy Wang, Thanasekaran Jayakumar, Duen-Suey Chou, Ching-Ya Ko, Ming-Jen Hsu, Cheng-Ying Hsieh
Published 2015-05-01

Reduction of NF-κB Signals in Platelets and Prolongation of Platelet Plug Formation against High Shear Flow in Whole Blood on Human Subject by Columbianadin

by Chih-Wei Hsia, Chih-Hao Yang, Joen-Rong Sheu, Chih-Hsuan Hsia, Cheng-Lin Tsai, Wei-Chieh Huang, Ting-Yu Chen, Thanasekaran Jayakumar, Periyakali Saravana Bhavan, Yi Chang
Published 2020-10-01

Comparative Proteomic Identification of Protein Disulphide Isomerase A6 Associated with Tert-Butylhydroperoxide-Induced Liver Injury in Rat Hepatocytes

by Chien-Heng Shen, Shui-Yi Tung, Wen-Shih Huang, Kam-Fai Lee, Yung-Yu Hsieh, Meng Chiao Hsieh, Cheng-Nan Chen, Hsing-Chun Kuo
Published 2018-03-01

A Novel Zak Knockout Mouse with a Defective Ribotoxic Stress Response

by Dakshina M. Jandhyala, John Wong, Nicholas J. Mantis, Bruce E. Magun, John M. Leong, Cheleste M. Thorpe
Published 2016-09-01

1-O-Hexyl-2,3,5-Trimethylhydroquinone Ameliorates l-DOPA-Induced Cytotoxicity in PC12 Cells

by Hyun Jin Park, Jong Koo Kang, Myung Koo Lee
Published 2019-03-01