Adding hydroxyurea in combination with ruxolitinib improves clinical responses in hyperproliferative forms of myelofibrosis

by Novella Pugliese, Claudia Giordano, Davide Nappi, Luigiana Luciano, Claudio Cerchione, Mario Annunziata, Beniamino Casale, Elena Crisà, Maria Rosaria Villa, Luca Pezzullo, Maria Iovine, Marco Picardi, Francesco Grimaldi, Fabrizio Pane, Vincenzo Martinelli
Published 2019-06-01

Inside Perspective of the Synthetic and Computational Toolbox of JAK Inhibitors: Recent Updates

by Adriana Coricello, Francesco Mesiti, Antonio Lupia, Annalisa Maruca, Stefano Alcaro
Published 2020-07-01

Two-Year Safety and Effectiveness of Peficitinib in Moderate-To-Severe Rheumatoid Arthritis: A Phase IIb, Open-Label Extension Study

by Mark C. Genovese, Maria W. Greenwald, Sergio R. Gutierrez-Ureña, Mario H. Cardiel, Jeffrey E. Poiley, Anna Zubrzycka-Sienkiewicz, Christine E. Codding, Annie Wang, Weizhong He, Rebecca Amos, Raul Vinueza, Xuegong Wang, Jay P. Garg, Alan J. Kivitz
Published 2019-08-01

At the crossroads of 2 alopecias: Androgenetic alopecia pattern of hair regrowth in patients with alopecia areata treated with oral Janus kinase inhibitors

by Katerina Yale, MD, Aunna Pourang, MD, Maksim V. Plikus, PhD, Natasha A. Mesinkovska, MD, PhD
Published 2020-05-01

Double Thrombosis- Interesting Case of Polycythemia Vera

by Subashini Subramanian, Siva Ranganathan Green
Published 2020-05-01

Phytochemicals Targeting JAK–STAT Pathways in Inflammatory Bowel Disease: Insights from Animal Models

by Sun Young Moon, Kwang Dong Kim, Jiyun Yoo, Jeong-Hyung Lee, Cheol Hwangbo
Published 2021-05-01

TYK2 in Tumor Immunosurveillance

by Anzhelika Karjalainen, Stephen Shoebridge, Milica Krunic, Natalija Simonović, Graham Tebb, Sabine Macho-Maschler, Birgit Strobl, Mathias Müller
Published 2020-01-01

Janus Kinase Inhibitors and Coronavirus Disease (COVID)-19: Rationale, Clinical Evidence and Safety Issues

by Milo Gatti, Eleonora Turrini, Emanuel Raschi, Piero Sestili, Carmela Fimognari
Published 2021-07-01

More Unnecessary Imaginary Worlds - Part 1: The Institute for Clinical and Economic Review’s Evidence Report on Janus Kinase (JAK) Inhibitors in Rheumatoid Arthritis

by Paul Langley
Published 2020-01-01

<i>Drosophila</i> Jak/STAT Signaling: Regulation and Relevance in Human Cancer and Metastasis

by Sunny Trivedi, Michelle Starz-Gaiano
Published 2018-12-01

Patient- and physician-reported outcomes from two phase 3 randomized studies (RAJ3 and RAJ4) of peficitinib (ASP015K) in Asian patients with rheumatoid arthritis

by Yoshiya Tanaka, Tsutomu Takeuchi, Hiroyuki Izutsu, Yuichiro Kaneko, Daisuke Kato, Musashi Fukuda, Mitsuhiro Rokuda, Neil M. Schultz
Published 2021-08-01

STAT3: Versatile Functions in Non-Small Cell Lung Cancer

by Julian Mohrherr, Iris Z. Uras, Herwig P. Moll, Emilio Casanova
Published 2020-04-01

Role of Janus-Kinases in Major Depressive Disorder

by Anne Gulbins, Heike Grassmé, Richard Hoehn, Marcus Kohnen, Michael J. Edwards, Johannes Kornhuber, Erich Gulbins
Published 2016-08-01

Role of JAK/STAT in Interstitial Lung Diseases; Molecular and Cellular Mechanisms

by Paula Montero, Javier Milara, Inés Roger, Julio Cortijo
Published 2021-06-01