Aspartic acid70 in the HLA-DRB1 chain and shared epitope alleles partially explain the high prevalence of autoimmunity in Mexicans

by Luis Francisco Valdés-Corona, Susana Hernández-Doño, Tatiana Sofia Rodríguez-Reyna, Rafael García-Silva, Juan Jakez, Monica Escamilla-Tilch, Guadalupe Lima, Luis Llorente, Carlos Pineda, Edmond Yunis, Julio Granados
Published 2020-01-01

Programmed death ligand 2 – A link between inflammation and bone loss in rheumatoid arthritis

by Stinne R. Greisen, Tue W. Kragstrup, Jesper Skovhus Thomsen, Aida Solhøj Hansen, Akilan Krishnamurthy, Kim Hørslev-Petersen, Merete Lund Hetland, Kristian Stengaard-Pedersen, Mikkel Østergaard, Lykke Midtbøll Ørnbjerg, Peter Junker, Arlene H. Sharpe, Gordon J. Freeman, Lakshmanan Annamalai, Malene Hvid, Søren K. Moestrup, Ellen-Margrethe Hauge, Anca Irinel Catrina, Bent Deleuran
Published 2020-01-01

Bcl-xL overexpression decreases GILZ levels and inhibits glucocorticoid-induced activation of caspase-8 and caspase-3 in mouse thymocytes

by Isabella Muscari, Sabrina Adorisio, Anna Marina Liberati, Trinh Thi Thuy, Tran Van Sung, Lorenza Cannarile, Emira Ayroldi, Carlo Riccardi, Domenico V. Delfino
Published 2020-01-01

cDC1 are required for the initiation of collagen-induced arthritis

by Maria Ines Ramos, Samuel Garcia, Boy Helder, Saida Aarrass, Kris. A. Reedquist, Sten E. Jacobsen, Paul Peter Tak, Maria Cristina Lebre
Published 2020-01-01

Antibody response to homologous epitopes of Epstein-Barr virus, Mycobacterium avium subsp. paratuberculosis and IRF5 in patients with different connective tissue diseases and in mo...

by Marco Bo, Magdalena Niegowska, Hayley L. Eames, Hannah Almuttaqi, Giannina Arru, Gian Luca Erre, Giuseppe Passiu, Tariq E. Khoyratty, Erinke van Grinsven, Irina A. Udalova, Leonardo A. Sechi
Published 2020-01-01

Pathogenic priming likely contributes to serious and critical illness and mortality in COVID-19 via autoimmunity

by James Lyons-Weiler
Published 2020-01-01

Immune-mediated genesis of multiple sclerosis

by Salvatore Cavallo, MD, Specialist in Medical Genetics
Published 2020-01-01

Testing for IgA anti-tissue transglutaminase in routine clinical practice: Requesting behaviour in relation to prevalence of positive results

by Maurits Damoiseaux, William van Doorn, Ellen van Lochem, Jan Damoiseaux
Published 2020-01-01

Comparative immunophenotyping of Saccharomyces cerevisiae and Candida spp. strains from Crohn’s disease patients and their interactions with the gut microbiome

by Monica Di Paola, Lisa Rizzetto, Irene Stefanini, Francesco Vitali, Cristina Massi-Benedetti, Noemi Tocci, Luigina Romani, Matteo Ramazzotti, Paolo Lionetti, Carlotta De Filippo, Duccio Cavalieri
Published 2020-01-01

Involvement of long noncoding RNAs in the pathogenesis of autoimmune diseases

by Yaoyao Zou, Hanshi Xu
Published 2020-01-01

Breakdown of T-cell ignorance: The tolerance failure responsible for mainstream autoimmune diseases?

by Myer R. Salaman, Keith G. Gould
Published 2020-01-01

Decreased HLA-DQ expression on peripheral blood cells in children with varying number of beta cell autoantibodies

by Agnes Andersson Svärd, Marlena Maziarz, Anita Ramelius, Markus Lundgren, Åke Lernmark, Helena Elding Larsson, C. Andersson, R. Bennet, I. Jönsson, M. Ask, J. Bremer, C. Brundin, C. Cilio, C. Hansson, G. Hansson, S. Ivarsson, B. Jonsdottir, B. Lindberg, B. Lernmark, J. Melin, A. Carlsson, E. Cedervall, B. Jönsson, K. Larsson, J. Neiderud
Published 2020-01-01

Immunological mechanism of IgG4-related disease

by Changyan Liu, Panpan Zhang, Wen Zhang
Published 2020-01-01

The effect of sex on immune responses to a homocitrullinated peptide in the DR4-transgenic mouse model of Rheumatoid Arthritis

by Ewa Cairns, Sheri Saunders, David A. Bell, Garth Blackler, Patrick Lac, Lillian Barra
Published 2020-01-01

Immunometabolism in the pathogenesis of systemic lupus erythematosus

by Chen-xing Zhang, Hui-yu Wang, Lei Yin, You-ying Mao, Wei Zhou
Published 2020-01-01

Dysregulation of glycerophospholipid metabolism during Behçet’s disease contributes to a pro-inflammatory phenotype of circulating monocytes

by Ana Mendes-Frias, Bruno Santos-Lima, Danielle Zildeana Sousa Furtado, Francisco J. Ruperez, Nilson Antonio Assunção, Maria João Matias, Vânia Gomes, Joana Gaifem, Coral Barbas, António Gil Castro, Carlos Capela, Ricardo Silvestre
Published 2020-01-01

Axenic Caenorhabditis elegans antigen protects against development of type-1 diabetes in NOD mice

by Belinda M. Jackson-Thompson, Marina Torrero, Blima K. Mitre, James Long, Mathanraj Packiam, Edward Mitre
Published 2020-01-01

Prevalence of autoantibody responses in acute coronavirus disease 2019 (COVID-19)

by L. Angelica Lerma, Anu Chaudhary, Andrew Bryan, Chihiro Morishima, Mark H. Wener, Susan L. Fink
Published 2020-01-01

Trisomy X in a patient with childhood-onset systemic lupus erythematosus

by Fernanda B. Barbosa, Nailu Angelica Sinicato, Paulo Rogério Julio, Ana Carolina Londe, Roberto Marini, Vera L. Gil-da-Silva-Lopes, Simone Appenzeller
Published 2020-01-01

CXCR3+ T cells in multiple sclerosis correlate with reduced diversity of the gut microbiome

by Siobhán Ní Choileáin, Markus Kleinewietfeld, Khadir Raddassi, David A. Hafler, William E. Ruff, Erin E. Longbrake
Published 2020-01-01