Optimizing the timing of diagnostic testing after positive findings in lung cancer screening: a proof of concept radiomics study

by Zixing Wang, Ning Li, Fuling Zheng, Xin Sui, Wei Han, Fang Xue, Xiaoli Xu, Cuihong Yang, Yaoda Hu, Lei Wang, Wei Song, Jingmei Jiang
Published 2021-05-01

Application of stem cell-derived exosomes in ischemic diseases: opportunity and limitations

by Majid Babaei, Jafar Rezaie
Published 2021-05-01

Metformin ameliorates scleroderma via inhibiting Th17 cells and reducing mTOR-STAT3 signaling in skin fibroblasts

by Jeonghyeon Moon, Seon-yeong Lee, Jeong Won Choi, A Ram Lee, Jin Hee Yoo, Su-Jin Moon, Sung-Hwan Park, Mi-La Cho
Published 2021-05-01

Sex specific trajectories of central adiposity, lipid indices, and glucose level with incident hypertension: 12 years Follow-up in Tehran lipid and glucose study

by Noushin Sadat Ahanchi, Seyed Saeed Tamehri Zadeh, Davood Khalili, Fereidoun Azizi, Farzad Hadaegh
Published 2021-02-01

Combined lymphocyte/monocyte count, D-dimer and iron status predict COVID-19 course and outcome in a long-term care facility

by Flavia Biamonte, Cirino Botta, Maria Mazzitelli, Salvatore Rotundo, Enrico Maria Trecarichi, Daniela Foti, Carlo Torti, Giuseppe Viglietto, Daniele Torella, Francesco Costanzo
Published 2021-02-01

Tumor immunogenomic signatures improve a prognostic model of melanoma survival

by Leah Morales, Danny Simpson, Robert Ferguson, John Cadley, Eduardo Esteva, Kelsey Monson, Vylyny Chat, Carlos Martinez, Jeffrey Weber, Iman Osman, Tomas Kirchhoff
Published 2021-02-01

One-tube SARS-CoV-2 detection platform based on RT-RPA and CRISPR/Cas12a

by Yangyang Sun, Lei Yu, Chengxi Liu, Shanting Ye, Wei Chen, Dechang Li, Weiren Huang
Published 2021-02-01

Role of SIK1 in the transition of acute kidney injury into chronic kidney disease

by Jinxiu Hu, Jiao Qiao, Qun Yu, Bing Liu, Junhui Zhen, Yue Liu, Qiqi Ma, Yanmei Li, Qianhui Wang, Cheng Wang, Zhimei Lv
Published 2021-02-01

A systematic review of nutraceutical interventions for mitochondrial dysfunctions in myalgic encephalomyelitis/chronic fatigue syndrome

by Rebekah Maksoud, Cassandra Balinas, Sean Holden, Hélène Cabanas, Donald Staines, Sonya Marshall-Gradisnik
Published 2021-02-01

Avelumab treatment in Italian patients with metastatic Merkel cell carcinoma: experience from an expanded access program

by Giovanni Grignani, Vanna Chiarion Sileni, Carmine Pinto, Roberta Depenni, Nicola Fazio, Luca Galli, Dario Giuffrida, Carlo Carnaghi, Domenico Ciliberto, Domenico C. Corsi, Paola Queirolo, Elena Benincasa, Filippo Venturini, Gennaro Fazzi, Nuno Costa, Paolo Antonio Ascierto
Published 2021-02-01

A nomogram to predict the high-risk RS in HR+/HER2-breast cancer patients older than 50 years of age

by Jing Yu, Jiayi Wu, Ou Huang, Jianrong He, Li Zhu, Weiguo Chen, Yafen Li, Xiaosong Chen, Kunwei Shen
Published 2021-02-01

Insulin treatment improves liver histopathology and decreases expression of inflammatory and fibrogenic genes in a hyperglycemic, dyslipidemic hamster model of NAFLD

by Victoria Svop Jensen, Christian Fledelius, Christina Zachodnik, Jesper Damgaard, Helle Nygaard, Kristina Steinicke Tornqvist, Rikke Kaae Kirk, Birgitte Martine Viuff, Erik Max Wulff, Jens Lykkesfeldt, Henning Hvid
Published 2021-02-01

Translational stem cell therapy: vascularized skin grafts in skin repair and regeneration

by Qian Hua Phua, Hua Alexander Han, Boon-Seng Soh
Published 2021-02-01

Exercise rescues mitochondrial coupling in aged skeletal muscle: a comparison of different modalities in preventing sarcopenia

by Colin Harper, Venkatesh Gopalan, Jorming Goh
Published 2021-02-01

Genome-wide analysis identifies critical DNA methylations within NTRKs genes in colorectal cancer

by Zijian Chen, Zenghong Huang, Yanxin Luo, Qi Zou, Liangliang Bai, Guannan Tang, Xiaolin Wang, Guangwen Cao, Meijin Huang, Jun Xiang, Huichuan Yu
Published 2021-02-01

Cross-talk between ANGPTL4 gene SNP Rs1044250 and weight management is a risk factor of metabolic syndrome

by Zhoujie Tong, Jie Peng, Hongtao Lan, Wenwen Sai, Yulin Li, Jiaying Xie, Yanmin Tan, Wei Zhang, Ming Zhong, Zhihao Wang
Published 2021-02-01

A theoretical model of health management using data-driven decision-making: the future of precision medicine and health

by Eva Kriegova, Milos Kudelka, Martin Radvansky, Jiri Gallo
Published 2021-02-01

Chimeric antigen receptor T cells engineered to secrete CD40 agonist antibodies enhance antitumor efficacy

by Yajun Zhang, Pei Wang, Tengjiao Wang, Yuan Fang, Yongmei Ding, Qijun Qian
Published 2021-02-01

Translational research in Uganda: linking basic science to bedside medicine in a resource limited setting

by Richard Kwizera, Emmanuel Mande, Denis Omali, Samuel Okurut, Sheila Nabweyambo, Rose Nabatanzi, Damalie Nakanjako, David B. Meya
Published 2021-02-01

ER resident protein 44 promotes malignant phenotype in nasopharyngeal carcinoma through the interaction with ATP citrate lyase

by Hui Tian, Si Shi, Bo You, Qicheng Zhang, Miao Gu, Yiwen You
Published 2021-02-01