Microglia reprogram metabolic profiles for phenotype and function changes in central nervous system

by Sheng Yang, Chuan Qin, Zi-Wei Hu, Luo-Qi Zhou, Hai-Han Yu, Man Chen, Dale B. Bosco, Wei Wang, Long-Jun Wu, Dai-Shi Tian
Published 2021-05-01

Temporal characterization of microglia/macrophage phenotypes in a mouse model of neonatal hypoxic-ischemic brain injury

by Nina Hellström Erkenstam, Peter L.P. Smith, Bobbi Fleiss, Syam Nair, Pernilla Svedin, Wei Wang, Martina Boström, Pierre Gressens, Henrik Hagberg, Kelly L Brown, Karin Sävman, Carina Mallard
Published 2016-12-01

Clemastine Alleviates Depressive-Like Behavior Through Reversing the Imbalance of Microglia-Related Pro-inflammatory State in Mouse Hippocampus

by Wen-Jun Su, Ting Zhang, Ting Zhang, Chun-Lei Jiang, Wei Wang
Published 2018-11-01

Polydatin Prevents Lipopolysaccharide (LPS)-Induced Parkinson's Disease via Regulation of the AKT/GSK3β-Nrf2/NF-κB Signaling Axis

by Bingxu Huang, Juxiong Liu, Tianyu Meng, Yuhang Li, Dewei He, Xin Ran, Guangxin Chen, Guangxin Chen, Wenjin Guo, Xingchi Kan, Shoupeng Fu, Wei Wang, Dianfeng Liu
Published 2018-11-01

Myricetin prevents dopaminergic neurons from undergoing neuroinflammation-mediated degeneration in a lipopolysaccharide-induced Parkinson’s disease model

by Bingxu Huang, Juxiong Liu, Dongxu Ma, Guangxin Chen, Wei Wang, Shoupeng Fu
Published 2018-06-01

Combination of Tramadol with Minocycline Exerted Synergistic Effects on a Rat Model of Nerve Injury-Induced Neuropathic Pain

by Xiao-Peng Mei, Lei Chen, Wei Wang, Dan Wu, Li-Ying Wang, Ting Zhang, Hui Zhang, Li-Xian Xu, Yun-Qing Li
Published 2012-09-01

Galangin Reduces the Loss of Dopaminergic Neurons in an LPS-Evoked Model of Parkinson’s Disease in Rats

by Guangxin Chen, Juxiong Liu, Liqiang Jiang, Xin Ran, Dewei He, Yuhang Li, Bingxu Huang, Wei Wang, Shoupeng Fu
Published 2017-12-01

Licochalcone A Prevents the Loss of Dopaminergic Neurons by Inhibiting Microglial Activation in Lipopolysaccharide (LPS)-Induced Parkinson’s Disease Models

by Bingxu Huang, Juxiong Liu, Chen Ju, Dongxue Yang, Guangxin Chen, Shiyao Xu, Yalong Zeng, Xuan Yan, Wei Wang, Dianfeng Liu, Shoupeng Fu
Published 2017-09-01

Vanillin Protects Dopaminergic Neurons against Inflammation-Mediated Cell Death by Inhibiting ERK1/2, P38 and the NF-κB Signaling Pathway

by Xuan Yan, Dian-Feng Liu, Xiang-Yang Zhang, Dong Liu, Shi-Yao Xu, Guang-Xin Chen, Bing-Xu Huang, Wen-Zhi Ren, Wei Wang, Shou-Peng Fu, Ju-Xiong Liu
Published 2017-02-01

Regulatory T cells protect against brain damage by alleviating inflammatory response in neuromyelitis optica spectrum disorder

by Xue Ma, Chuan Qin, Man Chen, Hai-Han Yu, Yun-Hui Chu, Ting-Jun Chen, Dale B. Bosco, Long-Jun Wu, Bi-Tao Bu, Wei Wang, Dai-Shi Tian
Published 2021-09-01

GLP-2 Attenuates LPS-Induced Inflammation in BV-2 Cells by Inhibiting ERK1/2, JNK1/2 and NF-κB Signaling Pathways

by Nan Li, Bo-Wen Liu, Wen-Zhi Ren, Ju-Xiong Liu, Su-Nan Li, Shou-Peng Fu, Ya-Long Zeng, Shi-Yao Xu, Xuan Yan, Ying-Jie Gao, Dian-Feng Liu, Wei Wang
Published 2016-02-01

Peiminine Protects Dopaminergic Neurons from Inflammation-Induced Cell Death by Inhibiting the ERK1/2 and NF-κB Signalling Pathways

by Guangxin Chen, Juxiong Liu, Liqiang Jiang, Xin Ran, Dewei He, Yuhang Li, Bingxu Huang, Wei Wang, Dianfeng Liu, Shoupeng Fu
Published 2018-03-01

Deficiency of the microglial Hv1 proton channel attenuates neuronal pyroptosis and inhibits inflammatory reaction after spinal cord injury

by Xuefei Li, Zhiyuan Yu, Weifeng Zong, Peng Chen, Jia Li, Minghuan Wang, Fengfei Ding, Minjie Xie, Wei Wang, Xiang Luo
Published 2020-09-01

Minocycline Attenuates Stress-Induced Behavioral Changes via Its Anti-inflammatory Effects in an Animal Model of Post-traumatic Stress Disorder

by Wei Wang, Rui Wang, Jingjing Xu, Xiaqing Qin, Hong Jiang, Arslan Khalid, Dexiang Liu, Fang Pan, Cyrus S. H. Ho, Roger C. M. Ho
Published 2018-11-01

The Rho-associated kinase inhibitors Y27632 and fasudil promote microglial migration in the spinal cord via the ERK signaling pathway

by Pei-Cai Fu, Rong-Hua Tang, Zhi-Yuan Yu, Min-Jie Xie, Wei Wang, Xiang Luo
Published 2018-01-01

Microglial Activation of GLP-1R Signaling in Neuropathic Pain Promotes Gene Expression Adaption Involved in Inflammatory Responses

by Le Ma, Peijun Ju, Wei Wang, Jinbao Wei, Weidi Wang, Mengjing Zhao, Khalil Ali Ahmad, Yongxiang Wang, Jinghong Chen
Published 2021-01-01

Soluble epoxide hydrolase inhibition Promotes White Matter Integrity and Long-Term Functional Recovery after chronic hypoperfusion in mice

by Yuxue Chen, Hao Tian, Ensheng Yao, Yeye Tian, Huaqiu Zhang, Li Xu, Zhiyuan Yu, Yongkang Fang, Wei Wang, Peng Du, Minjie Xie
Published 2017-08-01

Deficiency of TREK-1 potassium channel exacerbates blood-brain barrier damage and neuroinflammation after intracerebral hemorrhage in mice

by Yongkang Fang, Yeye Tian, Qibao Huang, Yue Wan, Li Xu, Wei Wang, Dengji Pan, Suiqiang Zhu, Minjie Xie
Published 2019-05-01