Dissection of the mutation accumulation process during bacterial range expansions

by Lars Bosshard, Stephan Peischl, Martin Ackermann, Laurent Excoffier
Published 2020-03-01

Harmful mutation load in the mitochondrial genomes of cattle breeds

by Sankar Subramanian
Published 2021-06-01

The roles of hybridization and habitat fragmentation in the evolution of Brazil’s enigmatic longwing butterflies, Heliconius nattereri and H. hermathena

by Darli Massardo, Nicholas W. VanKuren, Sumitha Nallu, Renato R. Ramos, Pedro G. Ribeiro, Karina L. Silva-Brandão, Marcelo M. Brandão, Marília B. Lion, André V. L. Freitas, Márcio Z. Cardoso, Marcus R. Kronforst
Published 2020-07-01

Complete pathological response following neoadjuvant FOLFOX chemotherapy in BRCA2-mutant locally advanced rectal cancer: a case report

by Zhenyu Lin, Junli Liu, Li Peng, Dejun Zhang, Ming Jin, Jing Wang, Jun Xue, Hongli Liu, Tao Zhang
Published 2018-12-01

The existence of species rests on a metastable equilibrium between inbreeding and outbreeding. An essay on the close relationship between speciation, inbreeding and recessive mutat...

by Joly Etienne
Published 2011-12-01

Bioinformatically predicted deleterious mutations reveal complementation in the interior spruce hybrid complex

by Gina L. Conte, Kathryn A. Hodgins, Sam Yeaman, Jon C. Degner, Sally N. Aitken, Loren H. Rieseberg, Michael C. Whitlock
Published 2017-12-01

Analysis of mutations in CDC27, CTBP2, HYDIN and KMT5A genes in carotid paragangliomas

by E. N. Lukyanova, A. V. Snezhkina, D. V. Kalinin, A. V. Pokrovsky, A. L. Golovyuk, O. A. Stepanov, E. A. Pudova, G. S. Razmakhaev, M. V. Orlova, A. P. Polyakov, M. V. Kiseleva, A. D. Kaprin, A. V. Kudryavtseva
Published 2018-09-01

Selection in males purges the mutation load on female fitness

by Karl Grieshop, Paul L. Maurizio, Göran Arnqvist, David Berger
Published 2021-08-01

Challenges and potential of PD-1/PD-L1 checkpoint blockade immunotherapy for glioblastoma

by Xin Wang, Gaochao Guo, Hui Guan, Yang Yu, Jie Lu, Jinming Yu
Published 2019-02-01

Tumor mutation burden and recurrent tumors in hereditary lung cancer

by Yi‐Chiung Hsu, Ya‐Hsuan Chang, Gee‐Chen Chang, Bing‐Ching Ho, Shin‐Sheng Yuan, Yu‐Cheng Li, Jhih‐Wun Zeng, Sung‐Liang Yu, Ker‐Chau Li, Pan‐Chyr Yang, Hsuan‐Yu Chen
Published 2019-05-01

Genetic load has potential in large populations but is realized in small inbred populations

by Samarth Mathur, J. Andrew DeWoody
Published 2021-06-01

Genomic subtyping of liver cancers with prognostic application

by Zhenggang Wu, Xi Long, Shui Ying Tsang, Taobo Hu, Jian-Feng Yang, Wai Kin Mat, Hongyang Wang, Hong Xue
Published 2020-01-01

Exosomes from Plasma of Neuroblastoma Patients Contain Doublestranded DNA Reflecting the Mutational Status of Parental Tumor Cells

by Chiara Degli Esposti, Barbara Iadarola, Simone Maestri, Cristina Beltrami, Denise Lavezzari, Martina Morini, Patrizia De Marco, Giovanni Erminio, Alberto Garaventa, Federico Zara, Massimo Delledonne, Marzia Ognibene, Annalisa Pezzolo
Published 2021-04-01

Women Born to Older Mothers Have Reduced Fertility. Evidence From a Natural Fertility Population

by Niels van den Berg, Ingrid K. van Dijk, Rick J. Mourits
Published 2021-03-01

Association of clock-like mutational signature with immune checkpoint inhibitor outcome in patients with melanoma and NSCLC

by Wei Chong, Zhe Wang, Liang Shang, Shengtao Jia, Jin Liu, Zhen Fang, Fengying Du, Hao Wu, Yang Liu, Yang Chen, Hao Chen
Published 2021-03-01

Identification of an Immune Signature Predicting Prognosis Risk and Lymphocyte Infiltration in Colon Cancer

by Xinyu Li, Xinyu Li, Dacheng Wen, Xiaokang Li, Xiaokang Li, Chunli Yao, Wei Chong, Wei Chong, Wei Chong, Hao Chen
Published 2020-09-01

Genomic Profiling Reveals the Molecular Landscape of Gastrointestinal Tract Cancers in Chinese Patients

by Chunrong Zhu, Liangjun Zhu, Yanhong Gu, Ping Liu, Xiaoling Tong, Guozhong Wu, Wenyu Zhu, Wenxiang Shen, Hua Bao, Xiangyuan Ma, Ruoying Yu, Xue Wu, Dongqin Zhu, Yongqian Shu, Jifeng Feng
Published 2021-09-01

Aristolochic Acid and Immunotherapy for Urothelial Carcinoma: Directions for unmet Needs

by Huang-Yu Yang, Chih-Chao Yang, Chao-Yi Wu, Li-Jen Wang, Kun-Lin Lu
Published 2019-06-01

POLQ Overexpression Is Associated with an Increased Somatic Mutation Load and PLK4 Overexpression in Lung Adenocarcinoma

by Kazuya Shinmura, Hisami Kato, Yuichi Kawanishi, Katsuhiro Yoshimura, Kazuo Tsuchiya, Yoshiyuki Takahara, Seiji Hosokawa, Akikazu Kawase, Kazuhito Funai, Haruhiko Sugimura
Published 2019-05-01

Ultra-Mutation in <i>IDH</i> Wild-Type Glioblastomas of Patients Younger than 55 Years is Associated with Defective Mismatch Repair, Microsatellite Instability, and Giant Cell Enri...

by Valeria Barresi, Michele Simbolo, Andrea Mafficini, Maria Liliana Piredda, Maria Caffo, Salvatore Massimiliano Cardali, Antonino Germanò, Sara Cingarlini, Claudio Ghimenton, Aldo Scarpa
Published 2019-08-01