The Therapeutic Effects and Mechanisms of Quercetin on Metabolic Diseases: Pharmacological Data and Clinical Evidence

by Huan Yi, Hengyang Peng, Xinyue Wu, Xinmei Xu, Tingting Kuang, Jing Zhang, Leilei Du, Gang Fan
Published 2021-01-01

Zebrafish Model for Screening Antiatherosclerosis Drugs

by Jichun Han, Rui Zhang, Xiaofeng Zhang, Jing Dong, Minghan Chen, Yumin Pan, Zixian Liao, Min Zhong, Jingwen He, Feiqiang Wang, Yunyun Yue, Jing Shang
Published 2021-01-01

Role of Polyphenols as Antioxidant Supplementation in Ischemic Stroke

by Yuan Zhou, Shanshan Zhang, Xiang Fan
Published 2021-01-01

Data-Driven Cluster Analysis of Oxidative Stress Indexes in relation to Vitamin D Level, Age, and Metabolic Control in Patients with Type 2 Diabetes on Metformin Therapy

by Milena M. Cojic, Aleksandra Klisic, Radivoj Kocic, Andrej Veljkovic, Gordana Kocic
Published 2021-01-01

Analysis of Molecular Mechanism of Erxian Decoction in Treating Osteoporosis Based on Formula Optimization Model

by Lang Yang, Liuyi Fan, Kexin Wang, Yupeng Chen, Lan Liang, Xuemei Qin, Aiping Lu, Peng Cao, Bin Yu, Daogang Guan, Junxiang Peng
Published 2021-01-01

Sirtuins: Potential Therapeutic Targets for Defense against Oxidative Stress in Spinal Cord Injury

by Jialiang Lin, Zhencheng Xiong, Jionghui Gu, Zhuoran Sun, Shuai Jiang, Dongwei Fan, Weishi Li
Published 2021-01-01

The Protective Effect of Aspirin Eugenol Ester on Oxidative Stress to PC12 Cells Stimulated with H2O2 through Regulating PI3K/Akt Signal Pathway

by Zhen-Dong Zhang, Ya-Jun Yang, Xi-Wang Liu, Zhe Qin, Shi-Hong Li, Li-Xia Bai, Jian-Yong Li
Published 2021-01-01

UNC5B Promotes Vascular Endothelial Cell Senescence via the ROS-Mediated P53 Pathway

by Zhen Yang, Han Li, Pengcheng Luo, Dan Yan, Ni Yang, Yucong Zhang, Yi Huang, Yu Liu, Le Zhang, Jinhua Yan, Cuntai Zhang
Published 2021-01-01

Resveratrol Alleviates 27-Hydroxycholesterol-Induced Senescence in Nerve Cells and Affects Zebrafish Locomotor Behavior via Activation of SIRT1-Mediated STAT3 Signaling

by Jiao Liu, Kailin Jiao, Qian Zhou, Jun Yang, Keke Yang, Chunyan Hu, Ming Zhou, Zhong Li
Published 2021-01-01

Pentoxifylline Enhances Antioxidative Capability and Promotes Mitochondrial Biogenesis in D-Galactose-Induced Aging Mice by Increasing Nrf2 and PGC-1α through the cAMP-CREB Pathway...

by Yu Wang, Tianyun Zhang, Hui Zhao, Chunxiao Qi, Xiaoming Ji, Hexin Yan, Rui Cui, Guoliang Zhang, Yunxiao Kang, Geming Shi
Published 2021-01-01

Pan-Cancer Analysis of the Prognostic and Immunological Role of HSF1: A Potential Target for Survival and Immunotherapy

by Fei Chen, Yumei Fan, Pengxiu Cao, Bing Liu, Jiajie Hou, Bo Zhang, Ke Tan
Published 2021-01-01

YAP-Dependent Induction of CD47-Enriched Extracellular Vesicles Inhibits Dendritic Cell Activation and Ameliorates Hepatic Ischemia-Reperfusion Injury

by Zenan Yuan, Linsen Ye, Xiao Feng, Tian Zhou, Yi Zhou, Shuguang Zhu, Changchang Jia, Haibo Li, Dongbo Qiu, Kun Li, Wei Liu, Yang Li, Hui Tang, Guoying Wang, Qi Zhang, Yang Yang, Guihua Chen, Hua Li
Published 2021-01-01

Natural Products for Neurodegeneration: Regulating Neurotrophic Signals

by Md Sahab Uddin, Abdullah Al Mamun, Md Motiar Rahman, Philippe Jeandet, Athanasios Alexiou, Tapan Behl, Md Shahid Sarwar, Eduardo Sobarzo-Sánchez, Ghulam Md Ashraf, Amany A. Sayed, Ghadeer M. Albadrani, Ilaria Peluso, Mohamed M. Abdel-Daim
Published 2021-01-01

The Combination Treatment of Curcumin and Probucol Protects Chondrocytes from TNF-α Induced Inflammation by Enhancing Autophagy and Reducing Apoptosis via the PI3K-Akt-mTOR Pathway...

by Guangtao Han, Yubiao Zhang, Haohuan Li
Published 2021-01-01

Loss of Function of von Hippel-Lindau Trigger Lipocalin 2-Dependent Inflammatory Responses in Cultured and Primary Renal Tubular Cells

by Chan-Yen Kuo, Valeria Chiu, Po-Chun Hsieh, Tien Hsu, Ting-Yun Lin
Published 2021-01-01

Deficiency of Antioxidative Paraoxonase 2 (Pon2) Leads to Increased Number of Phenotypic LT-HSCs and Disturbed Erythropoiesis

by Lisa Spiecker, Ines Witte, Julia Mehlig, Viral Shah, Markus Meyerhöfer, Patricia S. Haehnel, Victoria Petermann, Andrea Schüler, Piyush More, Nina Cabezas-Wallscheid, Sven Horke, Andrea Pautz, Andreas Daiber, Daniel Sasca, Thomas Kindler, Hartmut Kleinert
Published 2021-01-01

Spironolactone Ameliorates Senescence and Calcification by Modulating Autophagy in Rat Tendon-Derived Stem Cells via the NF-κB/MAPK Pathway

by Kai Xu, Changjian Lin, Diana Ma, Mengyao Chen, Xing Zhou, Yuzhe He, Safwat Adel Abdo Moqbel, Chiyuan Ma, Lidong Wu
Published 2021-01-01

Circular RNA Expression: Its Potential Regulation and Function in Abdominal Aortic Aneurysms

by Yanshuo Han, Hao Zhang, Ce Bian, Chen Chen, Simei Tu, Jiahui Guo, Yihao Wu, Dittmar Böckler, Jian Zhang
Published 2021-01-01

Ligase Pellino3 Regulates Macrophage Action and Survival in Response to VSV Infection in RIG-I-Dependent Path

by Patryk Reniewicz, Anna Kula, Edyta Makuch, Michał Ochnik, Tomasz Lipiński, Jakub Siednienko
Published 2021-01-01

Trends in Natural Nutrients for Oxidative Stress and Cell Senescence

by Navid Omidifar, Mohsen moghadami, Seyyed Mojtaba Mousavi, Seyyed Alireza Hashemi, Ahmad Gholami, Mansoureh Shokripour, Zahra Sohrabi
Published 2021-01-01