Genome-wide association study of resistance to Mycobacterium tuberculosis infection identifies a locus at 10q26.2 in three distinct populations.

by Jocelyn Quistrebert, Marianna Orlova, Gaspard Kerner, Le Thi Ton, Nguyễn Trong Luong, Nguyễn Thanh Danh, Quentin B Vincent, Fabienne Jabot-Hanin, Yoann Seeleuthner, Jacinta Bustamante, Stéphanie Boisson-Dupuis, Nguyen Thu Huong, Nguyen Ngoc Ba, Jean-Laurent Casanova, Christophe Delacourt, Eileen G Hoal, Alexandre Alcaïs, Vu Hong Thai, Lai The Thành, Laurent Abel, Erwin Schurr, Aurélie Cobat
Published 2021-03-01

Human genetic admixture.

by Katharine L Korunes, Amy Goldberg
Published 2021-03-01

Short-range template switching in great ape genomes explored using pair hidden Markov models.

by Conor R Walker, Aylwyn Scally, Nicola De Maio, Nick Goldman
Published 2021-03-01

Neuronal SKN-1B modulates nutritional signalling pathways and mitochondrial networks to control satiety.

by Nikolaos Tataridas-Pallas, Maximillian A Thompson, Alexander Howard, Ian Brown, Marina Ezcurra, Ziyun Wu, Isabel Goncalves Silva, Christopher D Saunter, Timo Kuerten, David Weinkove, T Keith Blackwell, Jennifer M A Tullet
Published 2021-03-01

Changes in both trans- and cis-regulatory elements mediate insecticide resistance in a lepidopteron pest, Spodoptera exigua.

by Bo Hu, He Huang, Songzhu Hu, Miaomiao Ren, Qi Wei, Xiangrui Tian, Mohammed Esmail Abdalla Elzaki, Chris Bass, Jianya Su, Subba Reddy Palli
Published 2021-03-01

Stability of the cytosine methylome during post-testicular sperm maturation in mouse.

by Carolina Galan, Ryan W Serra, Fengyun Sun, Vera D Rinaldi, Colin C Conine, Oliver J Rando
Published 2021-03-01

Reduction of WDR81 impairs autophagic clearance of aggregated proteins and cell viability in neurodegenerative phenotypes.

by Xuezhao Liu, Limin Yin, Tianyou Li, Lingxi Lin, Jie Zhang, Yang Li
Published 2021-03-01

Behavior of dicentric chromosomes in budding yeast.

by Diana Cook, Sarah Long, John Stanton, Patrick Cusick, Colleen Lawrimore, Elaine Yeh, Sarah Grant, Kerry Bloom
Published 2021-03-01

A transcription-centric model of SNP-age interaction.

by Kun Wang, Mahashweta Basu, Justin Malin, Sridhar Hannenhalli
Published 2021-03-01

The microcephaly gene Donson is essential for progenitors of cortical glutamatergic and GABAergic neurons.

by Sathish Venkataramanappa, Dagmar Schütz, Friederike Saaber, Praveen Ashok Kumar, Philipp Abe, Stefan Schulz, Ralf Stumm
Published 2021-03-01

Analysis of the SNARE Stx8 recycling reveals that the retromer-sorting motif has undergone evolutionary divergence.

by Francisco Yanguas, M-Henar Valdivieso
Published 2021-03-01

activin-2 is required for regeneration of polarity on the planarian anterior-posterior axis.

by Jennifer K Cloutier, Conor L McMann, Isaac M Oderberg, Peter W Reddien
Published 2021-03-01

Recent loss of the Dim2 DNA methyltransferase decreases mutation rate in repeats and changes evolutionary trajectory in a fungal pathogen.

by Mareike Möller, Michael Habig, Cécile Lorrain, Alice Feurtey, Janine Haueisen, Wagner C Fagundes, Alireza Alizadeh, Michael Freitag, Eva H Stukenbrock
Published 2021-03-01

Neuropeptide F signaling regulates parasitoid-specific germline development and egg-laying in Drosophila.

by Madhumala K Sadanandappa, Shivaprasad H Sathyanarayana, Shu Kondo, Giovanni Bosco
Published 2021-03-01

AMPK-dependent and -independent coordination of mitochondrial function and muscle fiber type by FNIP1.

by Liwei Xiao, Jing Liu, Zongchao Sun, Yujing Yin, Yan Mao, Dengqiu Xu, Lin Liu, Zhisheng Xu, Qiqi Guo, Chenyun Ding, Wanping Sun, Likun Yang, Zheng Zhou, Danxia Zhou, Tingting Fu, Wenjing Zhou, Yuangang Zhu, Xiao-Wei Chen, John Zhong Li, Shuai Chen, Xiaoduo Xie, Zhenji Gan
Published 2021-03-01

The capacity of origins to load MCM establishes replication timing patterns.

by Livio Dukaj, Nicholas Rhind
Published 2021-03-01

Assessing the co-variability of DNA methylation across peripheral cells and tissues: Implications for the interpretation of findings in epigenetic epidemiology.

by Eilis Hannon, Georgina Mansell, Emma Walker, Marta F Nabais, Joe Burrage, Agnieszka Kepa, Janis Best-Lane, Anna Rose, Suzanne Heck, Terrie E Moffitt, Avshalom Caspi, Louise Arseneault, Jonathan Mill
Published 2021-03-01

A loss-of-function mutation in RORB disrupts saltatorial locomotion in rabbits.

by Miguel Carneiro, Jennifer Vieillard, Pedro Andrade, Samuel Boucher, Sandra Afonso, José A Blanco-Aguiar, Nuno Santos, João Branco, Pedro J Esteves, Nuno Ferrand, Klas Kullander, Leif Andersson
Published 2021-03-01

The etiology of Down syndrome: Maternal MCM9 polymorphisms increase risk of reduced recombination and nondisjunction of chromosome 21 during meiosis I within oocyte.

by Upamanyu Pal, Pinku Halder, Anirban Ray, Sumantra Sarkar, Supratim Datta, Papiya Ghosh, Sujay Ghosh
Published 2021-03-01

A cohesin cancer mutation reveals a role for the hinge domain in genome organization and gene expression.

by Zachary M Carico, Holden C Stefan, Megan Justice, Askar Yimit, Jill M Dowen
Published 2021-03-01