The Emerging Role of microRNAs in Polyglutamine Diseases

by Xiaoyu Dong, Shuyan Cong
Published 2019-06-01

Population genetics of spinoсerebellar ataxias caused by polyglutamine expansions

by A. N. Shuvaev, O. S. Belozor, M. V. Smolnikova, D. A. Yakovleva, Andr. N. Shuvaev, O. M. Kazantseva, E. A. Pozhilenkova, O. I. Mozhei, S. Kasparov
Published 2019-07-01

Molecular Biology of Huntington’s Disease

by Nagehan Ersoy, A. Nazlı Başak
Published 2005-02-01

microRNA dysregulation in polyglutamine toxicity of TATA-box binding protein is mediated through STAT1 in mouse neuronal cells

by Reema Roshan, Ashwani Choudhary, Aksheev Bhambri, Bhawani Bakshi, Tanay Ghosh, Beena Pillai
Published 2017-08-01

Co-expression Patterns between ATN1 and ATXN2 Coincide with Brain Regions Affected in Huntington’s Disease

by Arlin Keo, Arlin Keo, N. Ahmad Aziz, Oleh Dzyubachyk, Jeroen van der Grond, Willeke M. C. van Roon-Mom, Boudewijn P. F. Lelieveldt, Boudewijn P. F. Lelieveldt, Boudewijn P. F. Lelieveldt, Marcel J. T. Reinders, Marcel J. T. Reinders, Ahmed Mahfouz, Ahmed Mahfouz
Published 2017-11-01

Midazolam Enhances Mutant Huntingtin Protein Accumulation via Impairment of Autophagic Degradation In Vitro

by Jiqian Zhang, Wei Dai, Pengcheng Geng, Li Zhang, Qilian Tan, Dan Cheng, Pengfei Wei, Zhilai Yang, Lei Zhang, Erwei Gu, Guanghong Xu, Chaozhao Liang, Xuesheng Liu
Published 2018-07-01

A Genome-Wide RNAi Screen for Modifiers of Polyglutamine-Induced Neurotoxicity in Drosophila

by Voßfeldt, Hannes
Published 2013

Inhibition of NF-κB in astrocytes is sufficient to delay neurodegeneration induced by proteotoxicity in neurons

by Y. X. Li, O. C. M. Sibon, P. F. Dijkers
Published 2018-09-01

Selective suppression of polyglutamine-expanded protein by lipid nanoparticle-delivered siRNA targeting CAG expansions in the mouse CNS

by Tomoki Hirunagi, Kentaro Sahashi, Kiyoshi Tachikawa, Angel I. Leu, Michelle Nguyen, Rajesh Mukthavaram, Priya P. Karmali, Padmanabh Chivukula, Genki Tohnai, Madoka Iida, Kazunari Onodera, Manabu Ohyama, Yohei Okada, Hideyuki Okano, Masahisa Katsuno
Published 2021-06-01

Dissecting the role of glutamine in seeding peptide aggregation

by Exequiel E. Barrera, Francesco Zonta, Sergio Pantano
Published 2021-01-01

Protein Aggregation Inhibitors as Disease-Modifying Therapies for Polyglutamine Diseases

by Eiko N. Minakawa, Yoshitaka Nagai, Yoshitaka Nagai
Published 2021-02-01

Occupational therapy in spinocerebellar ataxia type 3: an open-label trial

by R.C.R. Silva, J.A.M. Saute, A.C.F. Silva, A.C.O. Coutinho, M.L. Saraiva-Pereira, L.B. Jardim
Published 2010-06-01

Transcriptional Dysregulation and Post-translational Modifications in Polyglutamine Diseases: From Pathogenesis to Potential Therapeutic Strategies

by Chunchen Xiang, Shun Zhang, Xiaoyu Dong, Shuang Ma, Shuyan Cong
Published 2018-05-01

Regulation of mRNA translation by MID1: a common mechanism of expanded CAG repeat RNAs

by Nadine Griesche, Judith Schilling, Stephanie Weber, Marlena Rohm, Verena Pesch, Frank Matthes, Georg Auburger, Sybille Krauss
Published 2016-10-01

In Vitro Expansion of CAG, CAA, and Mixed CAG/CAA Repeats

by Grzegorz Figura, Edyta Koscianska, Wlodzimierz J. Krzyzosiak
Published 2015-08-01

INDUCTION OF THE HEAT SHOCK RESPONSE TO PROTECT AGAINST POLYGLUTAMINE DISEASES AND THE ROLE OF PROTEIN SUMOYLATION IN LAMINOPATHIES AND ALZHEIMER'S DISEASE

by Zhang, Yu-Qian
Published 2008

Mutant CAG Repeats Effectively Targeted by RNA Interference in SCA7 Cells

by Agnieszka Fiszer, Joanna P. Wroblewska, Bartosz M. Nowak, Wlodzimierz J. Krzyzosiak
Published 2016-12-01

Polyglutamine-Expanded Androgen Receptor Alteration of Skeletal Muscle Homeostasis and Myonuclear Aggregation Are Affected by Sex, Age and Muscle Metabolism

by Mathilde Chivet, Caterina Marchioretti, Marco Pirazzini, Diana Piol, Chiara Scaramuzzino, Maria Josè Polanco, Vanina Romanello, Emanuela Zuccaro, Sara Parodi, Maurizio D’Antonio, Carlo Rinaldi, Fabio Sambataro, Elena Pegoraro, Gianni Soraru, Udai Bhan Pandey, Marco Sandri, Manuela Basso, Maria Pennuto
Published 2020-01-01

Impaired ATF6α processing, decreased Rheb and neuronal cell cycle re-entry in Huntington's disease

by Maria Rosario Fernandez-Fernandez, Isidro Ferrer, Jose J. Lucas
Published 2011-01-01

Conformational distortions induced by periodically recurring A…A in d(CAG).d(CAG) provide stereochemical rationale for the trapping of MSH2.MSH3 in polyQ disorders

by Yogeeshwar Ajjugal, Thenmalarchelvi Rathinavelan
Published 2021-01-01