human 598 genetics 515 Humans 496 Article 467 controlled study 352 metabolism 310 nonhuman 274 male 244 female 237 gene expression 219 RNA 213 adult 187 Animals 183 animal 178 unclassified drug 173 Female 166 Male 151 microRNA 149 messenger RNA 146 gene expression regulation 131 pathology 125 mouse 118 human cell 115 COVID-19 114 MicroRNAs 113 protein expression 112 middle aged 110 real time polymerase chain reaction 106 SARS-CoV-2 105 upregulation 105