Preclinical and Clinical Status of PSMA-Targeted Alpha Therapy for Metastatic Castration-Resistant Prostate Cancer

by Asta Juzeniene, Vilde Yuli Stenberg, Øyvind Sverre Bruland, Roy Hartvig Larsen
Published 2021-02-01

Individual dosimetry system for targeted alpha therapy based on PHITS coupled with microdosimetric kinetic model

by Tatsuhiko Sato, Takuya Furuta, Yuwei Liu, Sadahiro Naka, Shushi Nagamori, Yoshikatsu Kanai, Tadashi Watabe
Published 2021-01-01

Efficient formation of inert Bi-213 chelates by tetraphosphorus acid analogues of DOTA: towards improved alpha-therapeutics

by Jakub Šimeček, Petr Hermann, Christof Seidl, Frank Bruchertseifer, Alfred Morgenstern, Hans-Jürgen Wester, Johannes Notni
Published 2018-08-01

Towards Targeted Alpha Therapy with Actinium-225: Chelators for Mild Condition Radiolabeling and Targeting PSMA—A Proof of Concept Study

by Falco Reissig, David Bauer, Kristof Zarschler, Zbynek Novy, Katerina Bendova, Marie-Charlotte Ludik, Klaus Kopka, Hans-Jürgen Pietzsch, Milos Petrik, Constantin Mamat
Published 2021-04-01

Design of a Thorium Metal Target for ²²⁵Ac Production at TRIUMF

by Andrew K.H. Robertson, Andrew Lobbezoo, Louis Moskven, Paul Schaffer, Cornelia Hoehr
Published 2019-02-01

What is the role of the bystander response in radionuclide therapies?

by Darren eBrady, Joe M O'Sullivan, Kevin M Prise
Published 2013-08-01

The potential and hurdles of Targeted Alpha Therapy - Clinical trials and beyond

by Jorgen eElgqvist, Sofia eFrost, Jean-Pierre ePouget, Per eAlbertsson
Published 2014-01-01

Targeted-Alpha-Therapy Combining Astatine-211 and anti-CD138 Antibody in A Preclinical Syngeneic Mouse Model of Multiple Myeloma Minimal Residual Disease

by Sébastien Gouard, Catherine Maurel, Séverine Marionneau-Lambot, Delphine Dansette, Clément Bailly, François Guérard, Nicolas Chouin, Ferid Haddad, Cyril Alliot, Joëlle Gaschet, Romain Eychenne, Françoise Kraeber-Bodéré, Michel Chérel
Published 2020-09-01

The Mode-of-Action of Targeted Alpha Therapy Radium-223 as an Enabler for Novel Combinations to Treat Patients with Bone Metastasis

by Mari I. Suominen, Timothy Wilson, Sanna-Maria Käkönen, Arne Scholz
Published 2019-08-01

Optimizing labelling conditions of 213Bi-DOTATATE for preclinical applications of peptide receptor targeted alpha therapy

by Ho Sze Chan, Erik de Blois, Mark W. Konijnenberg, Alfred Morgenstern, Frank Bruchertseifer, Jeffrey P. Norenberg, Fred J. Verzijlbergen, Marion de Jong, Wouter A. P. Breeman
Published 2016-05-01

Systemic Targeted Alpha Radiotherapy for Cancer

by Allan B. J.
Published 2013-09-01

Bismuth-213 for Targeted Radionuclide Therapy: From Atom to Bedside

by Stephen Ahenkorah, Irwin Cassells, Christophe M. Deroose, Thomas Cardinaels, Andrew R. Burgoyne, Guy Bormans, Maarten Ooms, Frederik Cleeren
Published 2021-04-01

Overview of the Most Promising Radionuclides for Targeted Alpha Therapy: The “Hopeful Eight”

by Romain Eychenne, Michel Chérel, Férid Haddad, François Guérard, Jean-François Gestin
Published 2021-06-01

Anti-tumor efficacy of a combination therapy with PD-L1 targeted alpha therapy and adoptive cell transfer of PD-1 deficient melanoma-specific human T-lymphocytes

by L Marotte, M Capitao, C Deleine, T Beauvais, G Cadiou, J. Perrin, M Chérel, E Scotet, Y Guilloux, F Bruchertseifer, A Morgenstern, A Jarry, J. Gaschet, N Labarriere
Published 2021-01-01

Evaluation of polydentate picolinic acid chelating ligands and an α-melanocyte-stimulating hormone derivative for targeted alpha therapy using ISOL-produced 225Ac

by Caterina F. Ramogida, Andrew K. H. Robertson, Una Jermilova, Chengcheng Zhang, Hua Yang, Peter Kunz, Jens Lassen, Ivica Bratanovic, Victoria Brown, Lily Southcott, Cristina Rodríguez-Rodríguez, Valery Radchenko, François Bénard, Chris Orvig, Paul Schaffer
Published 2019-08-01

Synergistic Effect of a HER2 Targeted Thorium-227 Conjugate in Combination with Olaparib in a BRCA2 Deficient Xenograft Model

by Katrine Wickstroem, Jenny Karlsson, Christine Ellingsen, Véronique Cruciani, Alexander Kristian, Urs B. Hagemann, Roger M. Bjerke, Olav B. Ryan, Lars Linden, Dominik Mumberg, Michael Brands, Alan Cuthbertson
Published 2019-10-01

Targeted alpha therapy with astatine-211-labeled anti-PSCA A11 minibody shows antitumor efficacy in prostate cancer xenografts and bone microtumors

by Tom A. Bäck, Karin Jennbacken, Malin Hagberg Thulin, Sture Lindegren, Holger Jensen, Tove Olafsen, Paul J. Yazaki, Stig Palm, Per Albertsson, Jan-Erik Damber, Anna M. Wu, Karin Welén
Published 2020-02-01

Progress in Targeted Alpha-Particle Therapy. What We Learned about Recoils Release from In Vivo Generators

by Ján Kozempel, Olga Mokhodoeva, Martin Vlk
Published 2018-03-01

LANTHANIDE-BASED CORE-SHELL NANOPARTICLES AS MULTIFUNCTIONAL PLATFORMS FOR TARGETED RADIONUCLIDE THERAPY AND MULTIMODAL MOLECULAR IMAGING

by Toro-Gonzalez, Miguel
Published 2018

Targeted Alpha Therapy: Progress in Radionuclide Production, Radiochemistry and Applications

by Bryce J. B. Nelson, Jan D. Andersson, Frank Wuest
Published 2021-12-01