human 14 Humans 13 tumor suppressor gene 13 Article 11 genetics 9 controlled study 8 adult 7 cell proliferation 5 gene expression 5 human cell 5 pathology 5 unclassified drug 5 upregulation 5 Cell Line, Tumor 4 Cell Proliferation 4 Gene Expression Regulation, Neoplastic 4 Middle Aged 4 down regulation 4 female 4 gene expression regulation 4 human tissue 4 major clinical study 4 male 4 middle aged 4 signal transduction 4 tumor cell line 4 Animals 3 Female 3 Male 3 animal 3