Minimum quality threshold in pre-clinical sepsis studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis

by Marcin F. Osuchowski, Alfred Ayala, Soheyl Bahrami, Michael Bauer, Mihaly Boros, Jean-Marc Cavaillon, Irshad H. Chaudry, Craig M. Coopersmith, Clifford Deutschman, Susanne Drechsler, Philip Efron, Claes Frostell, Gerhard Fritsch, Waldemar Gozdzik, Judith Hellman, Markus Huber-Lang, Shigeaki Inoue, Sylvia Knapp, Andrey V. Kozlov, Claude Libert, John C. Marshall, Lyle L. Moldawer, Peter Radermacher, Heinz Redl, Daniel G. Remick, Mervyn Singer, Christoph Thiemermann, Ping Wang, Willem Joost Wiersinga, Xianzhong Xiao, Basilia Zingarelli
Published 2018-08-01

Study protocol for a national cohort of adults focused on respiratory health: the American Lung Association Lung Health Cohort (ALA-LHC) Study

by Mercedes Carnethon, Mark T Dransfield, Mary B Rice, George R Washko, MeiLan K Han, Gerard Criner, Charlie Strange, Sonali Bose, Raul San Jose Estepar, Barry Make, Alejandro P. Comellas, Linda Rogers, Ravi Kalhan, Mario Castro, Nadia Hansel, Robert A. Wise, Elliot Israel, Joan Reibman, Murray Mittleman, Philip Diaz, Sandhya Khurana, Paul A Reyfman, Elizabeth Sugar, Heather Hazucha, Jenny Hixon, Curt Reynolds, Emily Dimango, Robert J. Kaner, Loretta G. Que, Jason Lang, Kathryn Blake, Allan J. Dozor, Jeremy Weingarten, James Moy, Michael Busk, Lynn B. Gerald, Monica Kraft, Igor Barjaktarevic, Stephen C. Lazarus, Edward T. Naureckas, Richard W. Vandivier, James Cury, Jerry A. Krishnan, M. Bradley Drummond, Frank C. Sciurba, Charles Irvin, Laura Feemster, Loren C. Denlinger, Katherine Cahill, Wendy C. Moore, William C. Bailey, Janet Holbrook, Alexandra Sierra, Susan Rappaport, Albert Rizzo
Published 2021-07-01

Epigallocatechin gallate from green tea effectively blocks infection of SARS-CoV-2 and new variants by inhibiting spike binding to ACE2 receptor

by Jinbiao Liu, Brittany H. Bodnar, Fengzhen Meng, Adil I. Khan, Xu Wang, Sami Saribas, Tao Wang, Saroj Chandra Lohani, Peng Wang, Zhengyu Wei, Jinjun Luo, Lina Zhou, Jianguo Wu, Guangxiang Luo, Qingsheng Li, Wenhui Hu, Wenzhe Ho
Published 2021-08-01

A Novel Human Long Noncoding RNA SCDAL Promotes Angiogenesis through SNF5‐Mediated GDF6 Expression

by Rongrong Wu, Wangxing Hu, Huan Chen, Yingchao Wang, Qingju Li, Changchen Xiao, Lin Fan, Zhiwei Zhong, Xiaoying Chen, Kaiqi Lv, Shuhan Zhong, Yanna Shi, Jinghai Chen, Wei Zhu, Jianyi Zhang, Xinyang Hu, Jian'an Wang
Published 2021-09-01

Early detection of ovarian cancer using the risk of ovarian cancer algorithm with frequent CA125 testing in women at increased familial risk-combined results from two screening tri...

by Skates, Steven J, Greene, Mark H., Buys, Saundra S, Mai, Phuong L, Brown, Powel, Piedmonte, Marion, Rodriguez, Gustavo, Schorge, John O, Sherman, Mark, Daly, Mary B, Rutherford, Thomas, Brewster, Wendy R, O'Malley, David M, Partridge, Edward, Boggess, John, Drescher, Charles W, Isaacs, Claudine, Berchuck, Andrew, Domchek, Susan, Davidson, Susan A, Edwards, Robert, Elg, Steven A, Wakeley, Katie, Phillips, Kelly-Anne, Armstrong, Debroah, Horowitz, Ira, Fabian Carol J, Walker, Joan, Sluss, Patrick M, Welch, William, Minasian, Lori, Horick, Nora K, Kasten, Carol H, Nayfield, Susan, Alberts, David, Finkelstein, Dianne M, Lu, Karen H
Published 2017

Current neurologic treatment and emerging therapies in CDKL5 deficiency disorder

by Heather E. Olson, Carolyn I. Daniels, Isabel Haviland, Lindsay C. Swanson, Caitlin A. Greene, Anne Marie M. Denny, Scott T. Demarest, Elia Pestana-Knight, Xiaoming Zhang, Ahsan N. Moosa, Andrea Fidell, Judith L. Weisenberg, Bernhard Suter, Cary Fu, Jeffrey L. Neul, Alan K. Percy, Eric D. Marsh, Timothy A. Benke, Annapurna Poduri
Published 2021-09-01

Splicing profile by capture RNA-seq identifies pathogenic germline variants in tumor suppressor genes

by Tyler Landrith, Bing Li, Ashley A. Cass, Blair R. Conner, Holly LaDuca, Danielle B. McKenna, Kara N. Maxwell, Susan Domchek, Nichole A. Morman, Christopher Heinlen, Deborah Wham, Cathryn Koptiuch, Jennie Vagher, Ragene Rivera, Ann Bunnell, Gayle Patel, Jennifer L. Geurts, Morgan M. Depas, Shraddha Gaonkar, Sara Pirzadeh-Miller, Rebekah Krukenberg, Meredith Seidel, Robert Pilarski, Meagan Farmer, Khateriaa Pyrtel, Kara Milliron, John Lee, Elizabeth Hoodfar, Deepika Nathan, Amanda C. Ganzak, Sitao Wu, Huy Vuong, Dong Xu, Aarani Arulmoli, Melissa Parra, Lily Hoang, Bhuvan Molparia, Michele Fennessy, Susanne Fox, Sinead Charpentier, Julia Burdette, Tina Pesaran, Jessica Profato, Brandon Smith, Ginger Haynes, Emily Dalton, Joy Rae-Radecki Crandall, Ruth Baxter, Hsiao-Mei Lu, Brigette Tippin-Davis, Aaron Elliott, Elizabeth Chao, Rachid Karam
Published 2020-02-01

Impact of PD-L1 and PD-1 Expression on the Prognostic Significance of CD8+ Tumor-Infiltrating Lymphocytes in Non-Small Cell Lung Cancer

by Enrico Munari, Enrico Munari, Marcella Marconi, Giulia Querzoli, Gianluigi Lunardi, Pietro Bertoglio, Francesco Ciompi, Alice Tosadori, Albino Eccher, Nicola Tumino, Linda Quatrini, Paola Vacca, Giulio Rossi, Alberto Cavazza, Guido Martignoni, Guido Martignoni, Matteo Brunelli, George J. Netto, Lorenzo Moretta, Giuseppe Zamboni, Giuseppe Zamboni, Giuseppe Bogina
Published 2021-05-01

Transcription Factor β-Catenin Plays a Key Role in Fluid Flow Shear Stress-Mediated Glomerular Injury in Solitary Kidney

by Tarak Srivastava, Daniel P. Heruth, R. Scott Duncan, Mohammad H. Rezaiekhaligh, Robert E. Garola, Lakshmi Priya, Jianping Zhou, Varun C. Boinpelly, Jan Novak, Mohammed Farhan Ali, Trupti Joshi, Uri S. Alon, Yuexu Jiang, Ellen T. McCarthy, Virginia J. Savin, Ram Sharma, Mark L. Johnson, Mukut Sharma
Published 2021-05-01

Cirrhosis in Hemochromatosis: Independent Risk Factors in 368 HFE p.C282Y Homozygotes

by James C. Barton, Christine E. McLaren, Wen-pin Chen, Grant A. Ramm, Gregory J. Anderson, Lawrie W. Powell, V. Nathan Subramaniam, Paul C. Adams, Pradyumna D. Phatak, Lyle C. Gurrin, John D. Phillips, Charles J. Parker, Mary J. Emond, Gordon D. McLaren
Published 2018-09-01

Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia

by Philip J. Law, Sonja I. Berndt, Helen E. Speedy, Nicola J. Camp, Georgina P. Sava, Christine F. Skibola, Amy Holroyd, Vijai Joseph, Nicola J. Sunter, Alexandra Nieters, Silvia Bea, Alain Monnereau, David Martin-Garcia, Lynn R. Goldin, Guillem Clot, Lauren R. Teras, Inés Quintela, Brenda M. Birmann, Sandrine Jayne, Wendy Cozen, Aneela Majid, Karin E. Smedby, Qing Lan, Claire Dearden, Angela R. Brooks-Wilson, Andrew G. Hall, Mark P. Purdue, Tryfonia Mainou-Fowler, Claire M. Vajdic, Graham H. Jackson, Pierluigi Cocco, Helen Marr, Yawei Zhang, Tongzhang Zheng, Graham G. Giles, Charles Lawrence, Timothy G. Call, Mark Liebow, Mads Melbye, Bengt Glimelius, Larry Mansouri, Martha Glenn, Karen Curtin, W Ryan Diver, Brian K. Link, Lucia Conde, Paige M. Bracci, Elizabeth A. Holly, Rebecca D. Jackson, Lesley F. Tinker, Yolanda Benavente, Paolo Boffetta, Paul Brennan, Marc Maynadie, James McKay, Demetrius Albanes, Stephanie Weinstein, Zhaoming Wang, Neil E. Caporaso, Lindsay M. Morton, Richard K. Severson, Elio Riboli, Paolo Vineis, Roel C. H. Vermeulen, Melissa C. Southey, Roger L. Milne, Jacqueline Clavel, Sabine Topka, John J. Spinelli, Peter Kraft, Maria Grazia Ennas, Geoffrey Summerfield, Giovanni M. Ferri, Robert J. Harris, Lucia Miligi, Andrew R. Pettitt, Kari E. North, David J. Allsup, Joseph F. Fraumeni, James R. Bailey, Kenneth Offit, Guy Pratt, Henrik Hjalgrim, Chris Pepper, Stephen J. Chanock, Chris Fegan, Richard Rosenquist, Silvia de Sanjose, Angel Carracedo, Martin J. S. Dyer, Daniel Catovsky, Elias Campo, James R. Cerhan, James M. Allan, Nathanial Rothman, Richard Houlston, Susan Slager
Published 2017-02-01

Incorporating kidney disease measures into cardiovascular risk prediction: Development and validation in 9 million adults from 72 datasets

by Kunihiro Matsushita, Simerjot K Jassal, Yingying Sang, Shoshana H Ballew, Morgan E Grams, Aditya Surapaneni, Johan Arnlov, Nisha Bansal, Milica Bozic, Hermann Brenner, Nigel J Brunskill, Alex R Chang, Rajkumar Chinnadurai, Massimo Cirillo, Adolfo Correa, Natalie Ebert, Kai-Uwe Eckardt, Ron T Gansevoort, Orlando Gutierrez, Farzad Hadaegh, Jiang He, Shih-Jen Hwang, Tazeen H Jafar, Takamasa Kayama, Csaba P Kovesdy, Gijs W Landman, Andrew S Levey, Donald M Lloyd-Jones, Rupert W. Major, Katsuyuki Miura, Paul Muntner, Girish N Nadkarni, David MJ Naimark, Christoph Nowak, Takayoshi Ohkubo, Michelle J Pena, Kevan R Polkinghorne, Charumathi Sabanayagam, Toshimi Sairenchi, Markus P Schneider, Varda Shalev, Michael Shlipak, Marit D Solbu, Nikita Stempniewicz, James Tollitt, José M Valdivielso, Joep van der Leeuw, Angela Yee-Moon Wang, Chi-Pang Wen, Mark Woodward, Kazumasa Yamagishi, Hiroshi Yatsuya, Luxia Zhang, Elke Schaeffner, Josef Coresh
Published 2020-10-01

Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices

by Pradeep Natarajan, Akhil Pampana, Sarah E. Graham, Sanni E. Ruotsalainen, James A. Perry, Paul S. de Vries, Jai G. Broome, James P. Pirruccello, Michael C. Honigberg, Krishna Aragam, Brooke Wolford, Jennifer A. Brody, Lucinda Antonacci-Fulton, Moscati Arden, Stella Aslibekyan, Themistocles L. Assimes, Christie M. Ballantyne, Lawrence F. Bielak, Joshua C. Bis, Brian E. Cade, Ron Do, Harsha Doddapaneni, Leslie S. Emery, Yi-Jen Hung, Marguerite R. Irvin, Alyna T. Khan, Leslie Lange, Jiwon Lee, Rozenn N. Lemaitre, Lisa W. Martin, Ginger Metcalf, May E. Montasser, Jee-Young Moon, Donna Muzny, Jeffrey R. O’Connell, Nicholette D. Palmer, Juan M. Peralta, Patricia A. Peyser, Adrienne M. Stilp, Michael Tsai, Fei Fei Wang, Daniel E. Weeks, Lisa R. Yanek, James G. Wilson, Goncalo Abecasis, Donna K. Arnett, Lewis C. Becker, John Blangero, Eric Boerwinkle, Donald W. Bowden, Yi-Cheng Chang, Yii-Der I. Chen, Won Jung Choi, Adolfo Correa, Joanne E. Curran, Mark J. Daly, Susan K. Dutcher, Patrick T. Ellinor, Myriam Fornage, Barry I. Freedman, Stacey Gabriel, Soren Germer, Richard A. Gibbs, Jiang He, Kristian Hveem, Gail P. Jarvik, Robert C. Kaplan, Sharon L. R. Kardia, Eimear Kenny, Ryan W. Kim, Charles Kooperberg, Cathy C. Laurie, Seonwook Lee, Don M. Lloyd-Jones, Ruth J. F. Loos, Steven A. Lubitz, Rasika A. Mathias, Karine A. Viaud Martinez, Stephen T. McGarvey, Braxton D. Mitchell, Deborah A. Nickerson, Kari E. North, Aarno Palotie, Cheol Joo Park, Bruce M. Psaty, D. C. Rao, Susan Redline, Alexander P. Reiner, Daekwan Seo, Jeong-Sun Seo, Albert V. Smith, Russell P. Tracy, Ramachandran S. Vasan, Sekar Kathiresan, L. Adrienne Cupples, Jerome I. Rotter, Alanna C. Morrison, Stephen S. Rich, Samuli Ripatti, Cristen Willer, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, FinnGen, Gina M. Peloso
Published 2021-04-01

CONQUEST Quality Standards: For the Collaboration on Quality Improvement Initiative for Achieving Excellence in Standards of COPD Care

by Pullen R, Miravitlles M, Sharma A, Singh D, Martinez F, Hurst JR, Alves L, Dransfield M, Chen R, Muro S, Winders T, Blango C, Muellerova H, Trudo F, Dorinsky P, Alacqua M, Morris T, Carter V, Couper A, Jones R, Kostikas K, Murray R, Price DB
Published 2021-08-01

Computer extracted gland features from H&E predicts prostate cancer recurrence comparably to a genomic companion diagnostic test: a large multi-site study

by Patrick Leo, Andrew Janowczyk, Robin Elliott, Nafiseh Janaki, Kaustav Bera, Rakesh Shiradkar, Xavier Farré, Pingfu Fu, Ayah El-Fahmawi, Mohammed Shahait, Jessica Kim, David Lee, Kosj Yamoah, Timothy R. Rebbeck, Francesca Khani, Brian D. Robinson, Lauri Eklund, Ivan Jambor, Harri Merisaari, Otto Ettala, Pekka Taimen, Hannu J. Aronen, Peter J. Boström, Ashutosh Tewari, Cristina Magi-Galluzzi, Eric Klein, Andrei Purysko, Natalie NC Shih, Michael Feldman, Sanjay Gupta, Priti Lal, Anant Madabhushi
Published 2021-05-01

A novel imaging based Nomogram for predicting post-surgical biochemical recurrence and adverse pathology of prostate cancer from pre-operative bi-parametric MRI

by Lin Li, Rakesh Shiradkar, Patrick Leo, Ahmad Algohary, Pingfu Fu, Sree Harsha Tirumani, Amr Mahran, Christina Buzzy, Verena C Obmann, Bahar Mansoori, Ayah El-Fahmawi, Mohammed Shahait, Ashutosh Tewari, Cristina Magi-Galluzzi, David Lee, Priti Lal, Lee Ponsky, Eric Klein, Andrei S. Purysko, Anant Madabhushi
Published 2021-01-01

Coffee and tea consumption in the early adult lifespan and left ventricular function in middle age: the CARDIA study

by Chike C. Nwabuo, Aisha S. Betoko, Jared P. Reis, Henrique T. Moreira, Henrique D. Vasconcellos, Eliseo Guallar, Christopher Cox, Stephen Sidney, Bharath Ambale‐Venkatesh, Cora E. Lewis, Pamela J. Schreiner, Donald Lloyd‐Jones, Catarina I. Kiefe, Samuel S. Gidding, João A.C. Lima
Published 2020-08-01

Serum thymidine kinase 1 activity as a pharmacodynamic marker of cyclin-dependent kinase 4/6 inhibition in patients with early-stage breast cancer receiving neoadjuvant palbociclib

by Nusayba Bagegni, Shana Thomas, Ning Liu, Jingqin Luo, Jeremy Hoog, Donald W. Northfelt, Matthew P. Goetz, Andres Forero, Mattias Bergqvist, Jakob Karen, Magnus Neumüller, Edward M. Suh, Zhanfang Guo, Kiran Vij, Souzan Sanati, Matthew Ellis, Cynthia X. Ma
Published 2017-11-01

Early Visual Processing Is Associated With Social Cognitive Performance in Recent-Onset Schizophrenia

by Amanda McCleery, Amanda McCleery, Amanda McCleery, Jonathan K. Wynn, Jonathan K. Wynn, Junghee Lee, Eric A. Reavis, Eric A. Reavis, Joseph Ventura, Kenneth L. Subotnik, Michael F. Green, Michael F. Green, Keith H. Nuechterlein, Keith H. Nuechterlein
Published 2020-08-01

Pimasertib Versus Dacarbazine in Patients With Unresectable <i>NRAS</i>-Mutated Cutaneous Melanoma: Phase II, Randomized, Controlled Trial with Crossover

by Celeste Lebbé, Caroline Dutriaux, Thierry Lesimple, Willem Kruit, Joseph Kerger, Luc Thomas, Bernard Guillot, Filippo de Braud, Claus Garbe, Jean-Jacques Grob, Carmen Loquai, Virginia Ferraresi, Caroline Robert, Paul Vasey, Robert Conry, Richard Isaacs, Enrique Espinosa, Armin Schueler, Giorgio Massimini, Brigitte Dréno
Published 2020-06-01