human 249 Article 200 Humans 176 controlled study 170 male 164 female 153 adult 117 metabolism 105 nonhuman 104 Male 100 Female 98 unclassified drug 97 Animals 83 animal 77 genetics 71 major clinical study 63 mouse 60 article 59 chemistry 53 animal experiment 51 pathology 51 Adult 50 middle aged 48 drug effect 46 Mice 44 Middle Aged 42 priority journal 39 protein expression 39 animal model 38 animal tissue 38