APACHE 8 adult 8 female 8 human 8 male 8 Article 7 major clinical study 7 Humans 6 controlled study 6 Female 5 Male 5 Middle Aged 5 blood 5 disease severity 5 middle aged 5 C reactive protein 4 intensive care unit 4 mortality 4 prediction 4 retrospective study 4 Adult 3 Sequential Organ Failure Assessment Score 3 Severity of Illness Index 3 aged 3 creatinine 3 critically ill patient 3 hospitalization 3 length of stay 3 leukocyte count 3 mortality rate 3