biological marker 294 human 287 Humans 249 Biomarkers 215 Article 175 female 173 male 162 adult 139 Female 136 controlled study 132 Male 121 middle aged 100 major clinical study 92 Adult 91 Middle Aged 91 blood 80 metabolism 78 aged 69 Aged 60 genetics 50 receiver operating characteristic 45 pathology 44 sensitivity and specificity 38 procedures 37 Case-Control Studies 36 case control study 36 young adult 36 Young Adult 34 adolescent 33 priority journal 33