Closed-loop control 10 Closed loop control systems 7 Article 4 Blood Glucose Self-Monitoring 4 Closed-loop 4 Diabetes Mellitus, Type 1 4 Humans 4 Hypoglycemic Agents 4 Insulin 4 Insulin Infusion Systems 4 adult 4 antidiabetic agent 4 blood glucose monitoring 4 glucose blood level 4 human 4 insulin 4 insulin dependent diabetes mellitus 4 insulin infusion 4 Adult 3 Blood Glucose 3 Controllers 3 Deep learning 3 Learning systems 3 Reinforcement learning 3 female 3 glucose 3 hypoglycemia 3 major clinical study 3 male 3 Actuators 2