Article 211 human 209 male 168 Humans 159 controlled study 158 female 144 adult 132 Male 92 dose response 84 nonhuman 79 Female 76 major clinical study 75 aged 66 middle aged 64 drug effect 59 animal experiment 58 unclassified drug 54 Animals 52 Middle Aged 52 priority journal 51 clinical article 50 Adult 49 Dose-Response Relationship, Drug 46 animal model 44 follow up 43 animal 41 low drug dose 41 treatment outcome 40 procedures 39 drug efficacy 38