Protein-based condensation mechanisms drive the assembly of RNA-rich P granules

by Helen Schmidt, Andrea Putnam, Dominique Rasoloson, Geraldine Seydoux
Published 2021-06-01

Dual targeting of salt inducible kinases and CSF1R uncouples bone formation and bone resorption

by Cheng-Chia Tang, Christian D Castro Andrade, Maureen J O'Meara, Sung-Hee Yoon, Tadatoshi Sato, Daniel J Brooks, Mary L Bouxsein, Janaina da Silva Martins, Jinhua Wang, Nathanael S Gray, Barbara Misof, Paul Roschger, Stephane Blouin, Klaus Klaushofer, Annegreet Velduis-Vlug, Yosta Vegting, Clifford J Rosen, Daniel O'Connell, Thomas B Sundberg, Ramnik J Xavier, Peter Ung, Avner Schlessinger, Henry M Kronenberg, Rebecca Berdeaux, Marc Foretz, Marc N Wein
Published 2021-06-01

Glycinergic axonal inhibition subserves acute spatial sensitivity to sudden increases in sound intensity

by Tom P Franken, Brian J Bondy, David B Haimes, Joshua H Goldwyn, Nace L Golding, Philip H Smith, Philip X Joris
Published 2021-06-01

Post-translational flavinylation is associated with diverse extracytosolic redox functionalities throughout bacterial life

by Raphaël Méheust, Shuo Huang, Rafael Rivera-Lugo, Jillian F Banfield, Samuel H Light
Published 2021-05-01

Spherical arena reveals optokinetic response tuning to stimulus location, size, and frequency across entire visual field of larval zebrafish

by Florian A Dehmelt, Rebecca Meier, Julian Hinz, Takeshi Yoshimatsu, Clara A Simacek, Ruoyu Huang, Kun Wang, Tom Baden, Aristides B Arrenberg
Published 2021-06-01

Alpha-1 adrenergic receptor antagonists to prevent hyperinflammation and death from lower respiratory tract infection

by Allison Koenecke, Michael Powell, Ruoxuan Xiong, Zhu Shen, Nicole Fischer, Sakibul Huq, Adham M Khalafallah, Marco Trevisan, Pär Sparen, Juan J Carrero, Akihiko Nishimura, Brian Caffo, Elizabeth A Stuart, Renyuan Bai, Verena Staedtke, David L Thomas, Nickolas Papadopoulos, Ken W Kinzler, Bert Vogelstein, Shibin Zhou, Chetan Bettegowda, Maximilian F Konig, Brett D Mensh, Joshua T Vogelstein, Susan Athey
Published 2021-06-01

Scaling of subcellular actin structures with cell length through decelerated growth

by Shane G McInally, Jane Kondev, Bruce L Goode
Published 2021-06-01

HP1α is a chromatin crosslinker that controls nuclear and mitotic chromosome mechanics

by Amy R Strom, Ronald J Biggs, Edward J Banigan, Xiaotao Wang, Katherine Chiu, Cameron Herman, Jimena Collado, Feng Yue, Joan C Ritland Politz, Leah J Tait, David Scalzo, Agnes Telling, Mark Groudine, Clifford P Brangwynne, John F Marko, Andrew D Stephens
Published 2021-06-01

Chitinase 3-like-1 contributes to acetaminophen-induced liver injury by promoting hepatic platelet recruitment

by Zhao Shan, Leike Li, Constance Lynn Atkins, Meng Wang, Yankai Wen, Jongmin Jeong, Nicolas F Moreno, Dechun Feng, Xun Gui, Ningyan Zhang, Chun Geun Lee, Jack A Elias, William M Lee, Bin Gao, Fong Wilson Lam, Zhiqiang An, Cynthia Ju
Published 2021-06-01

miR-125-chinmo pathway regulates dietary restriction-dependent enhancement of lifespan in Drosophila

by Manish Pandey, Sakshi Bansal, Sudipta Bar, Amit Kumar Yadav, Nicholas S Sokol, Jason M Tennessen, Pankaj Kapahi, Geetanjali Chawla
Published 2021-06-01

Thalamus and claustrum control parallel layer 1 circuits in retrosplenial cortex

by Ellen KW Brennan, Izabela Jedrasiak-Cape, Sameer Kailasa, Sharena P Rice, Shyam Kumar Sudhakar, Omar J Ahmed
Published 2021-06-01

The temporal representation of experience in subjective mood

by Hanna Keren, Charles Zheng, David C Jangraw, Katharine Chang, Aria Vitale, Robb B Rutledge, Francisco Pereira, Dylan M Nielson, Argyris Stringaris
Published 2021-06-01

Loss of heterozygosity results in rapid but variable genome homogenization across yeast genetic backgrounds

by Abhishek Dutta, Fabien Dutreux, Joseph Schacherer
Published 2021-06-01

5'-UTR SNP of FGF13 causes translational defect and intellectual disability

by Xingyu Pan, Jingrong Zhao, Zhiying Zhou, Jijun Chen, Zhenxing Yang, Yuxuan Wu, Meizhu Bai, Yang Jiao, Yun Yang, Xuye Hu, Tianling Cheng, Qianyun Lu, Bin Wang, Chang-Lin Li, Ying-Jin Lu, Lei Diao, Yan-Qing Zhong, Jing Pan, Jianmin Zhu, Hua-Sheng Xiao, Zi-Long Qiu, Jinsong Li, Zefeng Wang, Jingyi Hui, Lan Bao, Xu Zhang
Published 2021-06-01

Neural dynamics of semantic categorization in semantic variant of primary progressive aphasia

by V Borghesani, CL Dale, S Lukic, LBN Hinkley, M Lauricella, W Shwe, D Mizuiri, S Honma, Z Miller, B Miller, JF Houde, ML Gorno-Tempini, SS Nagarajan
Published 2021-06-01

A hypothesis on the capacity of plant odorant-binding proteins to bind volatile isoprenoids based on in silico evidences

by Deborah Giordano, Angelo Facchiano, Sabato D'Auria, Francesco Loreto
Published 2021-06-01

Intrinsic OXPHOS limitations underlie cellular bioenergetics in leukemia

by Margaret AM Nelson, Kelsey L McLaughlin, James T Hagen, Hannah S Coalson, Cameron Schmidt, Miki Kassai, Kimberly A Kew, Joseph M McClung, P Darrell Neufer, Patricia Brophy, Nasreen A Vohra, Darla Liles, Myles C Cabot, Kelsey H Fisher-Wellman
Published 2021-06-01

Going beyond lifestyle factors

by Milagros Ruiz
Published 2021-06-01

In silico analysis of the transcriptional regulatory logic of neuronal identity specification throughout the C. elegans nervous system

by Lori Glenwinkel, Seth R Taylor, Kasper Langebeck-Jensen, Laura Pereira, Molly B Reilly, Manasa Basavaraju, Ibnul Rafi, Eviatar Yemini, Roger Pocock, Nenad Sestan, Marc Hammarlund, David M Miller III, Oliver Hobert
Published 2021-06-01

The trajectory of cortical GABA across the lifespan, an individual participant data meta-analysis of edited MRS studies

by Eric C Porges, Greg Jensen, Brent Foster, Richard AE Edden, Nicolaas AJ Puts
Published 2021-06-01