Article 1 Critical ion-pairs concentration and equilibrium constant (Keq) 1 DNA protein complex 1 Ostwald's dilution law 1 Poly(ethylene oxide) 1 adaboost 1 artificial neural network 1 binding affinity 1 classification 1 comparative study 1 controlled study 1 correlation coefficient 1 cross validation 1 double stranded DNA 1 double stranded RNA 1 equilibrium constant 1 extreme gradient boosting 1 extremely randomized tree 1 feature selection 1 gradient boosting 1 k nearest neighbor 1 kernel method 1 missense mutation 1 multilayer perceptron 1 nucleic acid 1 physical chemistry 1 point mutation 1 prediction 1 protein DNA interaction 1 protein RNA binding 1