FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy

by Carlos J Diaz Osterman, Duygu Ozmadenci, Elizabeth G Kleinschmidt, Kristin N Taylor, Allison M Barrie, Shulin Jiang, Lisa M Bean, Florian J Sulzmaier, Christine Jean, Isabelle Tancioni, Kristen Anderson, Sean Uryu, Edward A Cordasco, Jian Li, Xiao Lei Chen, Guo Fu, Marjaana Ojalill, Pekka Rappu, Jyrki Heino, Adam M Mark, Guorong Xu, Kathleen M Fisch, Vihren N Kolev, David T Weaver, Jonathan A Pachter, Balázs Győrffy, Michael T McHale, Denise C Connolly, Alfredo Molinolo, Dwayne G Stupack, David D Schlaepfer
Published 2019-09-01

Involvement of the FAK Network in Pathologies Related to Altered Mechanotransduction

by Enrica Urciuoli, Barbara Peruzzi
Published 2020-12-01

FAK displacement from focal adhesions: a promising strategy to target processes implicated in cancer progression and metastasis

by Ioanna Antoniades, Maria Kyriakou, Anna Charalambous, Katerina Kalalidou, Andri Christodoulou, Maria Christoforou, Paris A. Skourides
Published 2021-01-01

Phagocyte Transcriptomic Analysis Reveals Focal Adhesion Kinase (FAK) and Heparan Sulfate Proteoglycans (HSPGs) as Major Regulators in Anti-bacterial Defense of Crassostrea hongkon...

by Yue Lin, Yue Lin, Fan Mao, Fan Mao, Fan Mao, Nai-Kei Wong, Xiangyu Zhang, Xiangyu Zhang, Kunna Liu, Kunna Liu, Minwei Huang, Minwei Huang, Minwei Huang, Haitao Ma, Haitao Ma, Haitao Ma, Zhiming Xiang, Zhiming Xiang, Zhiming Xiang, Jun Li, Jun Li, Jun Li, Shu Xiao, Shu Xiao, Shu Xiao, Yang Zhang, Yang Zhang, Yang Zhang, Ziniu Yu, Ziniu Yu, Ziniu Yu
Published 2020-03-01

FAK Shutdown: Consequences on Epithelial Morphogenesis and Biomarker Expression Involving an Innovative Biomaterial for Tissue Regeneration

by Xiaoling Wang, Thorsten Steinberg, Martin P. Dieterle, Imke Ramminger, Ayman Husari, Pascal Tomakidi
Published 2021-09-01

Downregulation of C-Terminal Tensin-Like Protein (CTEN) Suppresses Prostate Cell Proliferation and Contributes to Acinar Morphogenesis

by Wei-Ming Wu, Yi-Chun Liao
Published 2018-10-01

Heparin-Mimicking Polymer-Based In Vitro Platform Recapitulates In Vivo Muscle Atrophy Phenotypes

by Hyunbum Kim, Ji Hoon Jeong, Mona Fendereski, Hyo-Shin Lee, Da Yeon Kang, Sung Sik Hur, Jhaleh Amirian, Yunhye Kim, Nghia Thi Pham, Nayoung Suh, Nathaniel Suk-Yeon Hwang, Seongho Ryu, Jeong Kyo Yoon, Yongsung Hwang
Published 2021-03-01

Immune Cell Induced Migration of Osteoprogenitor Cells Is Mediated by TGF-β Dependent Upregulation of NOX4 and Activation of Focal Adhesion Kinase

by Sabrina Ehnert, Caren Linnemann, Romina H. Aspera-Werz, Daria Bykova, Sara Biermann, Leonie Fecht, Peter M. De Zwart, Andreas K. Nussler, Fabian Stuby
Published 2018-07-01

Atezolizumab potentiates Tcell-mediated cytotoxicity and coordinates with FAK to suppress cell invasion and motility in PD-L1+ triple negative breast cancer cells

by Nishant Mohan, Salman Hosain, Jun Zhao, Yi Shen, Xiao Luo, Jiangsong Jiang, Yukinori Endo, Wen Jin Wu
Published 2019-09-01

Resveratrol suppresses human colon cancer cell proliferation and induces apoptosis via targeting the pentose phosphate and the talin-FAK signaling pathways-A proteomic approach

by Reddivari Lavanya, Radhakrishnan Sridhar, Vanamala Jairam, Bhat Vadiraja B, Ptitsyn Andrey
Published 2011-08-01

Structure-Based Virtual Screening, Synthesis and Biological Evaluation of Potential FAK-FAT Domain Inhibitors for Treatment of Metastatic Cancer

by Sahar B. Kandil, Samuel R. Jones, Sonia Smith, Stephen E. Hiscox, Andrew D. Westwell
Published 2020-07-01

Impact of FAK Expression on the Cytotoxic Effects of CIK Therapy in Triple-Negative Breast Cancer

by Mei-Ren Pan, Cheng-Che Wu, Jung-Yu Kan, Qiao-Lin Li, Shu-Jyuan Chang, Chun-Chieh Wu, Chung-Liang Li, Fu Ou-Yang, Ming-Feng Hou, Hon-Kan Yip, Chi-Wen Luo
Published 2019-12-01

Characterization Of A Novel Genotype Rotavirus And Investigations On Signalling Pathways In Rotavirus Infected MA104 Cells

by Reddy, Yugandhar B S
Published 2013

Impaired Focal Adhesion Kinase-Grb2 Interaction during Elevated Activity in Hippocampal Neurons

by Sachiko Murase
Published 2015-07-01

FAK Deficiency in Bone Marrow Stromal Cells Alters Their Homeostasis and Drives Abnormal Proliferation and Differentiation of Haematopoietic Stem Cells

by Yuenv Wu, Lydia Campos, Elisabeth Daguenet, Zhiguo He, Tiphanie Picot, Emmanuelle Tavernier-Tardy, Gilbert Soglu, Denis Guyotat, Carmen-Mariana Aanei
Published 2020-03-01