gene editing 32 genetics 22 Gene Editing 20 CRISPR Cas system 19 CRISPR-Cas Systems 17 Article 12 human 12 nonhuman 12 Animals 10 animal 10 CRISPR-CAS9 system 8 Humans 8 clustered regularly interspaced short palindromic repeat 6 controlled study 6 guide RNA 6 CRISPR-Cas9 5 RNA, Guide 5 genome editing 5 metabolism 5 CRISPR/Cas9 4 Clustered Regularly Interspaced Short Palindromic Repeats 4 Mutation 4 gene function 4 gene mutation 4 mutation 4 procedures 4 CRISPR 3 DNA sequence 3 Plant Breeding 3 Plants, Genetically Modified 3