genetic model 9 human 7 Humans 6 Article 5 adult 5 controlled study 5 female 5 male 5 Female 4 Male 4 article 4 major clinical study 4 gene frequency 3 genetics 3 Adult 2 Child 2 Computer Simulation 2 Gene Frequency 2 Haplotypes 2 Models, Biological 2 Polymorphism, Single Nucleotide 2 allele 2 biological model 2 case control study 2 child 2 computer simulation 2 disease predisposition 2 gene 2 genetic association 2 genotype 2