A single amino acid difference between the intracellular domains of amyloid precursor protein and amyloid-like precursor protein 2 enables induction of synaptic depression and bloc...

by Emilie Trillaud-Doppia, Nicolas Paradis-Isler, Jannic Boehm
Published 2016-07-01

Notch1 binds and induces degradation of Snail in hepatocellular carcinoma

by Lim Seung-Oe, Kim Hyeon, Quan Xiaoyuan, Ahn Sun-Min, Kim Hongtae, Hsieh David, Seong Je Kyung, Jung Guhung
Published 2011-11-01

The intracellular loop of the glycine receptor:It´s not all about the size

by Georg eLanglhofer, Carmen eVillmann
Published 2016-06-01

LRP-1 and LRP-2 receptors function in the membrane neuron. Trafficking mechanisms and proteolytic processing in Alzheimer’s disease

by Carlos eSpuch, Saida eOrtolano, Carmen eNavarro
Published 2012-07-01

Hes1 oscillation frequency correlates with activation of neural stem cells

by Kaise, Takashi
Published 2021

APP intracellular domain derived from amyloidogenic β- and γ-secretase cleavage regulates neprilysin expression

by Marcus Otto Grimm, Janine eMett, Christoph Peter Stahlmann, Sven eGrösgen, Viola Jessica Haupenthal, Tamara eBlümel, Benjamin eHundsdörfer, Valerie Christin Zimmer, Nadine Tamara Mylonas, Heikki eTanila, Ulrike eMüller, Heike Sabine Grimm, Tobias eHartmann
Published 2015-05-01

Investigating the properties of the ZIP4 M3M4 domain in the presence and absence of zinc

by Nguyen, Tuong-Vi T
Published 2011

Manipulations of amyloid precursor protein cleavage disrupt the circadian clock in aging Drosophila

by Matthew R. Blake, Scott D. Holbrook, Joanna Kotwica-Rolinska, Eileen S. Chow, Doris Kretzschmar, Jadwiga M. Giebultowicz
Published 2015-05-01

Intracellular pH regulates amyloid precursor protein intracellular domain accumulation

by Valérie Vingtdeux, Malika Hamdane, Séverine Bégard, Anne Loyens, André Delacourte, Jean-Claude Beauvillain, Luc Buée, Philippe Marambaud, Nicolas Sergeant
Published 2007-03-01

EGFR protein expression using a specific intracellular domain antibody and PTEN and clinical outcomes in squamous cell lung cancer patients with EGFR-tyrosine kinase inhibitor ther...

by Chang H, Oh J, Zhang X, Kim YJ, Lee JH, Lee CT, Chung JH, Lee JS
Published 2016-08-01

Developmental signalling in maintenance and regulation of cancer stem cells

by Sweta Dash, Raghava Reddy Sunkara, Sanjeev K Waghmare
Published 2015-01-01

The Earliest T-Precursors in the Mouse Embryo Are Susceptible to Leukemic Transformation

by Jixin Ding, Angelo A. Cardoso, Angelo A. Cardoso, Momoko Yoshimoto, Momoko Yoshimoto, Michihiro Kobayashi, Michihiro Kobayashi
Published 2021-04-01

Molecular studies of the γ-secretase complex activity and selectivity towards the two substrates APP and Notch

by Bakir, Ilyas
Published 2010

Physiological effects of amyloid precursor protein and its derivatives on neural stem cell biology and signaling pathways involved

by Raquel Coronel, Charlotte Palmer, Adela Bernabeu-Zornoza, María Monteagudo, Andreea Rosca, Alberto Zambrano, Isabel Liste
Published 2019-01-01

Neuroprotective and Anti-Apoptotic Effects of CSP-1103 in Primary Cortical Neurons Exposed to Oxygen and Glucose Deprivation

by Vanessa Porrini, Ilenia Sarnico, Marina Benarese, Caterina Branca, Mariana Mota, Annamaria Lanzillotta, Arianna Bellucci, Edoardo Parrella, Lara Faggi, Pierfranco Spano, Bruno Pietro Imbimbo, Marina Pizzi
Published 2017-01-01

Cellular levels of Grb2 and cytoskeleton stability are correlated in a neurodegenerative scenario

by Piyali Majumder, Kasturi Roy, Brijesh Kumar Singh, Nihar Ranjan Jana, Debashis Mukhopadhyay
Published 2017-05-01

Notch1-Induced Survival Signaling And Its Implications In Cancer Therapeutics

by Mungamuri, Sathish Kumar
Published 2009

STRUCTURAL AND FUNCTIONAL STUDIES OF THE EFFECTS OF PHOSPHORYLATION ON EPHRIN RECEPTOR TYROSINE KINASE, EPHA2

by Javier, Fatima Raezelle Santos
Published 2018