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  1. 141
    Antiprotozoal and Antitumor Activity of Natural Polycyclic Endoperoxides: Origin, Structures and Biological Activity
    “... provides insights on further utilization of polycyclic endoperoxides by medicinal chemists, pharmacologists...”
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    Article
  2. 142
    An innovative strategy for dual inhibitor design and its application in dual inhibition of human thymidylate synthase and dihydrofolate reductase enzymes.
    “.... Nevertheless, to design multitarget inhibitors is concurrently a great challenge for medicinal chemists. We...”
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    Article
  3. 143
    Dual Inhibition of AChE and BChE with the C-5 Substituted Derivative of Meldrum’s Acid: Synthesis, Structure Elucidation, and Molecular Docking Studies
    “... to medicinal chemists, and the search for super-effective drugs for the treatment of AD is a work in progress...”
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    Article
  4. 144
    Use of structure-activity landscape index curves and curve integrals to evaluate the performance of multiple machine learning prediction models
    “... by medicinal chemists.</p> <p>Results</p> <p>The SALI approach was used to evaluate the performance...”
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    Article
  5. 145
    Cyclic Benzimidazole Derivatives and Their Antitumor Activity
    by Karminski-Zamola, G., Hranjec, M.
    Published 2008-06-01
    “... of heterocyclic compounds, and have received much attention from synthetic organic as well as medicinal chemists...”
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    Article
  6. 146
    Design, Synthesis and Screening of Peptidomimetics for Anticancer and Antiviral Drug Candidates
    by Liang, Yi
    Published 2016
    “... may be guided by rational design and molecular modeling. Now many organic and medicinal chemists have...”
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  7. 147
    Computational Insights on the Potential of Some NSAIDs for Treating COVID-19: Priority Set and Lead Optimization
    “... by medicinal chemists as lead compounds for the development of potent SARS-CoV-2 (M<sup>pro</sup>) inhibitors...”
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    Article
  8. 148
    SYNTHESIS OF N- ACETONITRIL AND N- ETHYLAMINE- 3- HYDROXYPYRIDINONES AS IRON (III) CHELATORS
    by L.A. SAGHAEI
    Published 2000-12-01
    “... balance. This metabolic behavior has led the medicinal chemists to design compounds such as N-hydroxyalkyl...”
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  9. 149
    Chemical Structure-Related Drug-Like Criteria of Global Approved Drugs
    by Fei Mao, Wei Ni, Xiang Xu, Hui Wang, Jing Wang, Min Ji, Jian Li
    Published 2016-01-01
    “... ADME/Tox properties, and ultimately affects its pharmacological activity. Medicinal chemists can...”
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    Article
  10. 150
    Synthesis, Anti-Inflammatory and Anti- Nociceptive Activities and Cytotoxic Effect of Novel Thiazolidin-4-ones Derivatives as Selective Cyclooxygenase (COX-2) Inhibitors
    “... to this, medicinal chemists have attempted to synthesize new classes of COX-2 Inhibitors.   Materials and Methods...”
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    Article
  11. 151
    Could α-Synuclein Modulation of Insulin and Dopamine Identify a Novel Link Between Parkinson’s Disease and Diabetes as Well as Potential Therapies?
    “...-Martinez et al., 2016). In collaboration with medicinal chemists, we made two non-immunosuppressive FTY720...”
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    Article
  12. 152
    Data mining for lead optimisation
    by Papadatos, George
    Published 2011
    “... answer to the real-life issues routinely facing medicinal chemists. The thesis is divided into three...”
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  13. 153
    Synthetic and physical properties studies on nanogold cluster of alkylthiol derived diaryl ether analogues
    by Ming-Che Kuo, 郭鳴哲
    Published 2012
    “... is an important target for medicinal chemists, and the antimiotic inhibitors suppress the microtubules in cell...”
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  14. 154
    Research of modern chain pharmacy introduce infant formula milk powder marketing
    by Chen-Chang Chu, 朱振昌
    Published 2005
    “... pharmacy stores, the more frequency that they interacted with medicine chemists. ...”
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  15. 155
    A fragment based approach to the development of novel antibacterial agents inspired by the natural product simocyclinone D8
    by Austin, Michael
    Published 2015
    “...The novel mechanism of simocyclinone D8 (SD8) against DNA gyrase has inspired medicinal chemists...”
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  16. 156
    Computation of hydrogen bond basicity as a descriptor in bioisosterism : a quantum chemical topology perspective
    by Green, Anthony James
    Published 2013
    “..., the pKBHX scale is claimed to be the most relevant to medicinal chemists because it gives a...”
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  17. 157
    Identification of Potential Binders of Mtb Universal Stress Protein (Rv1636) Through an in silico Approach and Insights Into Compound Selection for Experimental Validation
    “... provides an important initial guidance to medicinal chemists and biochemists to synthesize and test...”
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    Article
  18. 158
    Development and application of chemical tools for the design and synthesis of bioactive molecules
    by Lawandi, Janice
    Published 2010
    “...In the field of drug design and development, medicinal chemists use a variety of tools to quickly...”
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  19. 159
    Identification of a kinase profile that predicts chromosome damage induced by small molecule kinase inhibitors.
    “... a panel of kinases predictive of genotoxicity, we provide medicinal chemists a set of kinases...”
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    Article
  20. 160
    Challenging the Drug-Likeness Dogma for New Drug Discovery in Tuberculosis
    “.... Nevertheless, in the “instruction manual” of medicinal chemists, certain functional groups or certain...”
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    Article
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