Excessive mitochondrial fragmentation triggered by erlotinib promotes pancreatic cancer PANC-1 cell apoptosis via activating the mROS-HtrA2/Omi pathways

by Jun Wan, Jie Cui, Lei Wang, Kunpeng Wu, Xiaoping Hong, Yulin Zou, Shuang Zhao, Hong Ke
Published 2018-10-01

A Combined Phytochemistry and Network Pharmacology Approach to Reveal the Potential Antitumor Effective Substances and Mechanism of Phellinus igniarius

by Yu Dong, Yu Dong, Ping Qiu, Rui Zhu, Lisha Zhao, Pinghu Zhang, Yiqi Wang, Changyu Li, Kequn Chai, Kequn Chai, Kequn Chai, Dan Shou, Huajun Zhao
Published 2019-03-01

BAX Redistribution Induces Apoptosis Resistance and Selective Stress Sensitivity in Human HCC

by Kathrin Funk, Carolin Czauderna, Ramona Klesse, Diana Becker, Jovana Hajduk, Aline Oelgeklaus, Frank Reichenbach, Franziska Fimm-Todt, Joachim Lauterwasser, Peter R. Galle, Jens U. Marquardt, Frank Edlich
Published 2020-05-01

Adapentpronitrile, a New Dipeptidyl Peptidase-IV Inhibitor, Ameliorates Diabetic Neuronal Injury Through Inhibiting Mitochondria-Related Oxidative Stress and Apoptosis

by Lu Yang, Wenli Han, Ying Luo, Xiangnan Hu, Ying Xu, Huan Li, Congli Hu, Dan Huang, Jie Ma, Yang Yang, Qi Chen, Yuke Li, Jiahua Zhang, Hui Xia, Zhihao Chen, Hong Wang, Dongzhi Ran, Junqing Yang
Published 2018-07-01

microRNA-26a induces a mitochondrial apoptosis mediated by p53 through targeting to inhibit Mcl1 in human hepatocellular carcinoma

by Gao X, Zhu Y, Li JH, Wang X, Zhang X, Yi C, Yang X
Published 2018-04-01

Apoptosis induction activity of polysaccharide from Lentinus edodes in H22-bearing mice through ROS-mediated mitochondrial pathway and inhibition of tubulin polymerization

by Qilin Zhang, Zhaosong Du, Yu Zhang, Ziming Zheng, Qiang Li, Kaiping Wang
Published 2020-10-01

Isoforsythiaside Attenuates Alzheimer's Disease Via Regulating Mitochondrial Function Through the PI3K/AKT Pathway

by Chunyue Wang, Jie Hao, Xin Liu, Chenliang Li, Xuyang Yuan, Robert J. Lee, Tian Bai, Di Wang
Published 2020-08-01

Omentin-1 effects on mesenchymal stem cells: proliferation, apoptosis, and angiogenesis in vitro

by Li Yin, Dan Huang, Xinxin Liu, Yongshun Wang, Jingjin Liu, Fang Liu, Bo Yu
Published 2017-10-01

The Key Roles of GSK-3β in Regulating Mitochondrial Activity

by Kai Yang, Zhixi Chen, Juanjuan Gao, Weimei Shi, Linfu Li, Shan Jiang, Haibo Hu, Zhiping Liu, Daohua Xu, Longhuo Wu
Published 2017-12-01

Hepatitis E Virus Induces Brain Injury Probably Associated With Mitochondrial Apoptosis

by Jijing Tian, Ruihan Shi, Ruihan Shi, Peng Xiao, Tianlong Liu, Ruiping She, Qiaoxing Wu, Junqing An, Wenzhuo Hao, MajidHussain Soomro
Published 2019-12-01

A Homogeneous Polysaccharide from Fructus Schisandra chinensis (Turz.) Baill Induces Mitochondrial Apoptosis through the Hsp90/AKT Signalling Pathway in HepG2 Cells

by Yonglin Chen, Songshan Shi, Huijun Wang, Ning Li, Juan Su, Guixin Chou, Shunchun Wang
Published 2016-06-01

Potential Antitumor Effects of 6-Gingerol in p53-Dependent Mitochondrial Apoptosis and Inhibition of Tumor Sphere Formation in Breast Cancer Cells

by Nipin Sp, Dong Young Kang, Jin-Moo Lee, Se Won Bae, Kyoung-Jin Jang
Published 2021-04-01

Mitochondrial MPTP: A Novel Target of Ethnomedicine for Stroke Treatment by Apoptosis Inhibition

by Yangxin Li, Jiayi Sun, Ruixia Wu, Jinrong Bai, Ya Hou, Yong Zeng, Yi Zhang, Yi Zhang, Xiaobo Wang, Zhang Wang, Xianli Meng, Xianli Meng
Published 2020-03-01

Artesunate Activates the Intrinsic Apoptosis of HCT116 Cells through the Suppression of Fatty Acid Synthesis and the NF-κB Pathway

by Xiao Chen, Yin Kwan Wong, Teck Kwang Lim, Wei Hou Lim, Qingsong Lin, Jigang Wang, Zichun Hua
Published 2017-08-01

Neuroprotection of Strongylocentrotus nudus gangliosides against Alzheimer’s disease via regulation of neurite loss and mitochondrial apoptosis

by Xiaoxu Wang, Suyuan Tao, Peixu Cong, Yuming Wang, Jie Xu, Changhu Xue
Published 2017-06-01

Haploinsufficiency of NR3C1 drives glucocorticoid resistance in adult acute lymphoblastic leukemia cells by down-regulating the mitochondrial apoptosis axis, and is sensitive to Bc...

by Haowen Xiao, Yingying Ding, Yang Gao, Li-Mengmeng Wang, Huafang Wang, Lijuan Ding, Xiaoqing Li, Xiaohong Yu, He Huang
Published 2019-08-01

Silver Nanoparticle-Induced Apoptosis in ARPE-19 Cells Is Inhibited by Toxoplasma gondii Pre-Infection Through Suppression of NOX4-Dependent ROS Generation

by Quan JH, Gao FF, Ismail HAHA, Yuk JM, Cha GH, Chu JQ, Lee YH
Published 2020-05-01

Baicalin suppresses proliferation, migration, and invasion in human glioblastoma cells via Ca2+-dependent pathway

by Zhu Y, Fang J, Wang H, Fei M, Tang T, Liu K, Niu W, Zhou Y
Published 2018-10-01

Panax notoginseng saponins reduces the cisplatin-induced acute renal injury by increasing HIF-1α/BNIP3 to inhibit mitochondrial apoptosis pathway

by Qingqing Li, Yansong Zhang, Yufang Yang, Songqing Huang, Xiaoqin Zou, Congying Wei, Taolin Liang, Xiaobin Zhong
Published 2021-10-01

<i>Bmapaf-1</i> is Involved in the Response against BmNPV Infection by the Mitochondrial Apoptosis Pathway

by Xue-yang Wang, Xin-yi Ding, Qian-ying Chen, Kai-xiang Zhang, Chun-xiao Zhao, Xu-dong Tang, Yang-chun Wu, Mu-wang Li
Published 2020-09-01