Humans 90 Middle Aged human 90 middle aged 90 adult 88 female 88 Female 87 Male 85 male 85 Article 83 receiver operating characteristic 78 major clinical study 72 controlled study 68 aged 50 Aged 46 ROC Curve 44 Adult 41 sensitivity and specificity 39 blood 37 diagnostic test accuracy study 33 prognosis 28 pathology 27 Prognosis 26 risk factor 26 genetics 24 procedures 24 unclassified drug 24 Case-Control Studies 22 area under the curve 22 case control study 22