adult human 182 female 167 Article 160 male 159 receiver operating characteristic 147 Humans 145 controlled study 142 major clinical study 125 Female 108 middle aged 100 Male 97 Middle Aged 88 sensitivity and specificity 78 aged 70 Adult 68 ROC Curve 59 diagnostic test accuracy study 58 blood 47 Aged 46 area under the curve 38 procedures 37 prognosis 37 unclassified drug 37 pathology 36 predictive value 35 retrospective study 34 risk factor 34 biological marker 33 diagnostic value 32