male human 180 female 175 adult 159 Article 158 controlled study 146 Humans 144 receiver operating characteristic 141 major clinical study 123 Male 116 Female 108 middle aged 95 Middle Aged 85 sensitivity and specificity 77 aged 72 diagnostic test accuracy study 58 Adult 54 ROC Curve 50 Aged 48 blood 41 procedures 41 area under the curve 38 pathology 36 prognosis 36 retrospective study 36 risk factor 36 clinical article 33 biological marker 32 predictive value 31 unclassified drug 31