human 285 Article 240 receiver operating characteristic 222 Humans 221 controlled study 204 female 201 male 191 adult 189 major clinical study 148 Female 128 Male 116 sensitivity and specificity 111 middle aged 102 Middle Aged 90 ROC Curve 85 diagnostic test accuracy study 84 aged 78 Adult 68 procedures 63 area under the curve 62 blood 57 genetics 53 machine learning 53 Aged 52 article 51 biological marker 48 pathology 47 prediction 47 nonhuman 44 clinical article 43