protein expression Article 61 human 52 signal transduction 48 controlled study 47 metabolism 38 nonhuman 37 Humans 36 human cell 28 upregulation 26 male 25 unclassified drug 25 mouse 24 Western blotting 22 animal experiment 22 genetics 22 Animals 21 animal 21 animal model 20 female 19 gene expression 19 Signal Transduction 18 animal cell 17 down regulation 17 pathology 16 adult 15 protein function 15 animal tissue 14 apoptosis 14 protein kinase B 14