Is blood pressure reduction a valid surrogate endpoint for stroke prevention? an analysis incorporating a systematic review of randomised controlled trials, a by-trial weighted err...

by Lassere Marissa N, Johnson Kent R, Schiff Michal, Rees David
Published 2012-03-01

Searching for potential surrogate endpoints of overall survival in clinical trials for patients with prostate cancer

by Hideki Maeda, Kentaro Takeda, Hisashi Urushihara, Tatsuo Kurokawa
Published 2021-06-01

Prognostic and therapeutic implications of measurable residual disease in acute myeloid leukemia

by Marisa J. L. Aitken, Farhad Ravandi, Keyur P. Patel, Nicholas J. Short
Published 2021-09-01

Progression-free survival as a surrogate endpoint of overall survival in patients with metastatic colorectal cancer

by Cicero G, De Luca R, Dieli F
Published 2018-05-01

Comparison of Clopidogrel and Ticlopidine/Ginkgo Biloba in Patients With Clopidogrel Resistance and Carotid Stenting

by Jong-Won Chung, Suk Jae Kim, Jaechun Hwang, Mi Ji Lee, Jun Lee, Kyung-Yul Lee, Man-Seok Park, Sang Min Sung, Keon Ha Kim, Pyoung Jeon, Oh Young Bang
Published 2019-01-01

Food and Drug Administration approvals in phase 3 Cancer clinical trials

by Joseph Abi Jaoude, Ramez Kouzy, Marc Ghabach, Roshal Patel, Dario Pasalic, Elie Ghossain, Austin B. Miller, Timothy A. Lin, Vivek Verma, C. David Fuller, Vivek Subbiah, Bruce D. Minsky, Ethan B. Ludmir, Cullen M. Taniguchi
Published 2021-06-01

Evaluation of Therapeutic Strategies to Reduce the Number of Thrombotic Events in Patients With Polycythemia Vera and Essential Thrombocythemia

by Douglas Tremblay, Heidi E. Kosiorek, Amylou C. Dueck, Ronald Hoffman
Published 2021-02-01

Assessing correlates of protection in vaccine trials: statistical solutions in the context of high vaccine efficacy

by Andrea Callegaro, Fabian Tibaldi
Published 2019-03-01

Pre-existing chikungunya virus neutralizing antibodies correlate with risk of symptomatic infection and subclinical seroconversion in a Philippine cohort

by In-Kyu Yoon, Anon Srikiatkhachorn, Maria Theresa Alera, Stefan Fernandez, Derek A.T. Cummings, Henrik Salje
Published 2020-06-01

The potential investment impact of improved access to accelerated approval on the development of treatments for low prevalence rare diseases

by Kakkis Emil D, Miyamoto Brigitta E
Published 2011-07-01

Response Adaptive Randomization using Surrogate and Primary Endpoints

by Wang, Hui
Published 2016

Surrogate endpoint evaluation using data from one large global randomized controlled trial

by Milan Geybels, Benjamin Ole Wolthers, Frederik Flindt Kreiner, Søren Rasmussen, Robert Bauer
Published 2021-05-01

Imputation of a true endpoint from a surrogate: application to a cluster randomized controlled trial with partial information on the true endpoint

by Duffy Stephen W, Nixon Richard M, Fender Guy RK
Published 2003-09-01

Perspectives to mitigate payer uncertainty in health technology assessment of novel oncology drugs

by Oriol Solà-Morales, Timm Volmer, Lorenzo Mantovani
Published 2019-01-01

Progression-free survival/time to progression as a potential surrogate for overall survival in HR+, HER2– metastatic breast cancer

by Forsythe A, Chandiwana D, Barth J, Thabane M, Baeck J, Tremblay G
Published 2018-05-01

Effect of estimating equations for glomerular filtration rate on novel surrogate markers for renal outcome

by Kipyo Kim, Eunji Baek, Suryeong Go, Hyung-Eun Son, Ji-Young Ryu, Yongjin Yi, Jong Cheol Jeong, Sejoong Kim, Ho Jun Chin
Published 2021-06-01

CLINICAL SYMPTOMS AND MICROBIOLOGICAL OUTCOMES IN TUBERCULOSIS TREATMENT TRIALS

by Bark, Charles
Published 2011

EVENT-DRIVEN STUDIES AND SERIOUS CHRONIC DISEASES: ADDRESSING PLACEBO, DRUG EFFICACY, AND TREATMENT FAILURE IN PULMONARY ARTERY HYPERTENSION

by Henning Gall, Paul Corris
Published 2014-10-01

Evaluation of the effectiveness of lipid-lowering agents

by V. G. Shevko, M. A. Galas, T. L. Galankin, A. S. Kolbin
Published 2020-02-01

Combining Correlated Outcomes and Surrogate Endpoints in a Network Meta-Analysis of Colorectal Cancer Treatments

by Tung Hoang, Jeongseon Kim
Published 2020-09-01