human 179 Humans 145 female 139 male 127 adult 125 Article 118 Female 99 Male 92 Adult 76 controlled study 74 major clinical study 73 symptom 60 middle aged 48 aged 46 psychology 46 young adult 46 Young Adult 43 Middle Aged 42 depression 42 adolescent 41 Adolescent 40 child 38 pathophysiology 37 clinical article 33 disease severity 33 Child 31 Aged 29 priority journal 29 nuclear magnetic resonance imaging 28 questionnaire 28