Inhibitory Effects of Auraptene and Naringin on Astroglial Activation, Tau Hyperphosphorylation, and Suppression of Neurogenesis in the Hippocampus of Streptozotocin-Induced Hyperg...

by Satoshi Okuyama, Tatsumi Nakashima, Kumi Nakamura, Wakana Shinoka, Maho Kotani, Atsushi Sawamoto, Mitsunari Nakajima, Yoshiko Furukawa
Published 2018-08-01

Altered protein phosphatase 2A methylation and Tau phosphorylation in the young and aged brain of methylenetetrahydrofolate reductase (MTHFR) deficient mice

by Jean-Marie eSontag, Brandi eWasek, Goce eTaleski, Josephine eSmith, Erland eArning, Estelle eSontag, Teodoro eBottiglieri
Published 2014-08-01

Impacts of Acute Hypoxia on Alzheimer's Disease-Like Pathologies in APPswe/PS1dE9 Mice and Their Wild Type Littermates

by Feng Zhang, Feng Zhang, Rujia Zhong, Rujia Zhong, Hongqian Qi, Hongqian Qi, Song Li, Song Li, Cheng Cheng, Cheng Cheng, Xinyao Liu, Xinyao Liu, Yufei Liu, Yufei Liu, Weidong Le, Weidong Le, Weidong Le
Published 2018-05-01

MAPT R406W increases tau T217 phosphorylation in absence of amyloid pathology

by Chihiro Sato, Nipun Mallipeddi, Nupur Ghoshal, Brenton A. Wright, Gregory S. Day, Albert A. Davis, Albert H. Kim, Gregory J. Zipfel, Randall J. Bateman, Audrey Gabelle, Nicolas R. Barthélemy
Published 2021-09-01

Familial knockin mutation of LRRK2 causes lysosomal dysfunction and accumulation of endogenous insoluble α-synuclein in neurons

by Jason Schapansky, Saurabh Khasnavis, Mark P. DeAndrade, Jonathan D. Nardozzi, Samuel R. Falkson, Justin D. Boyd, John B. Sanderson, Tim Bartels, Heather L. Melrose, Matthew J. LaVoie
Published 2018-03-01

Sitagliptin increases tau phosphorylation in the hippocampus of rats with type 2 diabetes and in primary neuron cultures

by Dong-Hou Kim, Jae-Wan Huh, Mi Jang, Jung-Hyun Suh, Tae-Wan Kim, Jeong-Su Park, Seung-Yong Yoon
Published 2012-04-01

Antisense Oligonucleotide-Mediated Reduction of HDAC6 Does Not Reduce Tau Pathology in P301S Tau Transgenic Mice

by Antonio Valencia, Veronica L. Reinhart Bieber, Bekim Bajrami, Galina Marsh, Stefan Hamann, Ru Wei, Karen Ling, Frank Rigo, H. Moore Arnold, Olga Golonzhka, Heike Hering
Published 2021-06-01

Oxidative Stress Signaling in Blast TBI-Induced Tau Phosphorylation

by Chunyu Wang, Changjuan Shao, Li Zhang, Sandra L. Siedlak, James S. Meabon, Elaine R. Peskind, Yubing Lu, Wenzhang Wang, George Perry, David G. Cook, Xiongwei Zhu
Published 2021-06-01

Amyloid-β Oligomers Unveil a Novel Primate Model of Sporadic Alzheimer’s Disease

by Joseph eJebelli, Thomas ePiers
Published 2015-03-01

“Don’t Phos Over Tau”: recent developments in clinical biomarkers and therapies targeting tau phosphorylation in Alzheimer’s disease and other tauopathies

by Yuxing Xia, Stefan Prokop, Benoit I. Giasson
Published 2021-06-01

Interaction of Tau with Fe65 links tau to APP

by Christian Barbato, Nadia Canu, Nicola Zambrano, Annalucia Serafino, Giuseppina Minopoli, Maria Teresa Ciotti, Giuseppina Amadoro, Tommaso Russo, Pietro Calissano
Published 2005-03-01

Alzheimer’s disease brain contains tau fractions with differential prion-like activities

by Longfei Li, Ruirui Shi, Jianlan Gu, Yunn Chyn Tung, Yan Zhou, Dingwei Zhou, Ruozhen Wu, Dandan Chu, Nana Jin, Kevin Deng, Jiawei Xu, Cheng-Xin Gong, Khalid Iqbal, Fei Liu
Published 2021-02-01

Defined Tau Phosphospecies Differentially Inhibit Fast Axonal Transport Through Activation of Two Independent Signaling Pathways

by Sarah L. Morris, Sarah L. Morris, Ming-Ying Tsai, Sarah Aloe, Karin Bechberger, Svenja König, Gerardo Morfini, Gerardo Morfini, Scott T. Brady, Scott T. Brady
Published 2021-01-01

The Wnt/β-catenin signaling pathway affects the distribution of cytoskeletal proteins in Aβ treated PC12 cells

by Zhifeng Tian, Xiaoling Zhang, Zhijun Zhao, Fuhua Zhang, Tongxing Deng
Published 2019-09-01

Biochemical distribution of tau protein in synaptosomal fraction of transgenic mice expressing human P301L tau

by Naruhiko eSahara, Naruhiko eSahara, Miyuki eMurayama, Makoto eHiguchi, Suhara eTetsuya, Akihiko eTakashima, Akihiko eTakashima
Published 2014-03-01

Alzheimer’s disease: pathogenesis, diagnostics, and therapeutics

by Tiwari S, Atluri V, Kaushik A, Yndart A, Nair M
Published 2019-07-01

Tau phosphorylation induced by severe closed head traumatic brain injury is linked to the cellular prion protein

by Richard Rubenstein, Binggong Chang, Natalia Grinkina, Eleanor Drummond, Peter Davies, Meir Ruditzky, Deep Sharma, Kevin Wang, Thomas Wisniewski
Published 2017-04-01

Recent Developments of Protein Kinase Inhibitors as Potential AD Therapeutics

by Andreas eHilgeroth, Volkmar eTell
Published 2013-11-01

Cell-based Models To Investigate Tau Aggregation

by Sungsu Lim, Md. Mamunul Haque, Dohee Kim, Dong Jin Kim, Yun Kyung Kim
Published 2014-11-01

Differential Hyperphosphorylation of Tau-S199, -T231 and -S396 in Organotypic Brain Slices of Alzheimer Mice. A Model to Study Early Tau Hyperphosphorylation Using Okadaic Acid

by Bettina M. Foidl, Christian Humpel
Published 2018-04-01