Establishment of patient-derived organoids and a characterization-based drug discovery platform for treatment of pancreatic cancer

by Hatano, E., Kodo, T., Masui, T., Oishi, J., Otsubo, T., Seno, H., Takaishi, S., Uemoto, S., Umehara, H., Watanabe, S., Yogo, A.
Published 2022

Machine-learning aided in situ drug sensitivity screening predicts treatment outcomes in ovarian PDX tumors

by Ahn, S., Bashyam, A., Christodoulopoulos, E., Cima, M.J, Cotler, M.J, Ding, H., Hou, X., Jonas, O., Kaufmann, S.H, Larson, M., Oberg, A.L, Ramadi, K.B, Weroha, S.J, Whittaker, C.
Published 2022

Fast lightweight accurate xenograft sorting

by Rahmann, S., Zentgraf, J.
Published 2021

Plocabulin, a Novel Tubulin Inhibitor, Has Potent Antitumour Activity in Patient-Derived Xenograft Models of Soft Tissue Sarcoma

by Avilés, P., Cornillie, J., Debiec-Rychter, M., Schöffski, P., Sciot, R., Wang, Y., Wozniak, A.
Published 2022

Characterisation of 3D Bioprinted Human Breast Cancer Model for In Vitro Drug and Metabolic Targeting

by Dankó, T., Krencz, I., Moldvai, D., Pápay, J., Petővári, G., Raffay, R., Rókusz, A., Sebestyén, A., Sipos, K., Sztankovics, D., Vetlényi, E., Visnovitz, T.
Published 2022

Pre-Clinical Study Evaluating Novel Protein Phosphatase 2A Activators as Therapeutics for Neuroblastoma

by Aye, J.M, Beierle, A.M, Beierle, E.A, Bownes, L.V, Erwin, M.H, Hutchins, S.C, Julson, J.R, Marayati, R., Mroczek-Musulman, E., Ohlmeyer, M., Quinn, C.H, Stewart, J.E, Yoon, K.J
Published 2022

The Tumor Microenvironment Drives Intrahepatic Cholangiocarcinoma Progression

by Ardito, F., Armentano, R., Coletta, S., Dituri, F., Fabregat, I., Giannelli, G., Mancarella, S., Ruzzenente, A., Serino, G.
Published 2022

The Tumor Microenvironment Drives Intrahepatic Cholangiocarcinoma Progression

by Ardito, F., Armentano, R., Coletta, S., Dituri, F., Fabregat, I., Giannelli, G., Mancarella, S., Ruzzenente, A., Serino, G.
Published 2022

Establishment of Novel Neuroendocrine Carcinoma Patient-Derived Xenograft Models for Receptor Peptide-Targeted Therapy

by Abusada, E., Aghaamiri, S., Azhdarinia, A., Bellizzi, A.M, Beyer, G.V, Borbon, L.C, Chan, C.H.F, Cliften, P.F, Ear, P.H, Fields, R.C, Ghosh, S.C, Govindan, R., Howe, J.R, Li, G., Li, R., McDonough, M., Mudd, J.L, O’dorisio, M.S, O’dorisio, T., Tran, C.G, Vargas, S.H, Wadas, T.J, Walsh, S.A
Published 2022

ROADMAPS: An Online Database of Response Data, Dosing Regimens, and Toxicities of Approved Oncology Drugs as Single Agents to Guide Preclinical In Vivo Studies

by Camalier, R., Collins, J.M, Doroshow, J.H, Gottholm-Ahalt, M., Greenberg, N., Hollingshead, M.G, Johnson, B.C
Published 2022

Camptothecin Delivery via Tumor-Derived Exosome for Radiosensitization by Cell Cycle Regulation on Patient-Derived Xenograft Mice

by Dong, J., Guo, J., Huang, W., Ren, S., Yang, Y., Zhang, Y., Zhao, J.
Published 2022

Prostaglandin EP4 Selective Agonist AKDS001 Enhances New Bone Formation by Minimodeling in a Rat Heterotopic Xenograft Model of Human Bone

by Bal, Z., Fujimori, T., Hirai, H., Kaito, T., Kanie, Y., Kodama, J., Makino, T., Nakagawa, S., Nishida, M., Okada, S., Sakai, Y., Sakamoto, K., Takenaka, S., Takeyama, K., Tateiwa, D., Ukon, Y., Yamamori, N.
Published 2022

Non–beta blocker enantiomers of propranolol and atenolol inhibit vasculogenesis in infantile hemangioma

by Bischoff, J., Fontaine, F., Francois, M., Graus, M.S, Huang, L., Karnezis, T., McCann, A., Meunier, F., Mulliken, J.B, Seebauer, C.T, Staffa, S.J, Wylie-Sears, J., Zurakowski, D.
Published 2022

Enapotamab Vedotin, an AXL-Specific Antibody-Drug Conjugate, Demonstrates Antitumor Efficacy in Patient-Derived Xenograft Models of Soft Tissue Sarcoma

by Castro, P.G, Franken, P., Pencheva, N., Renterghem, B.V, Schöffski, P., Sciot, R., Wozniak, A.
Published 2022

Expression-based species deconvolution and realignment removes misalignment error in multispecies single-cell data

by Cho, S., Choi, J., Choi, S.M, Chung, J.-H, Kim, J.-I, Lee, C.-H, Lee, W., Moon, H.-G, Yang, H.-K, Yoon, J.-K
Published 2022

The Effect of Low-Processing Temperature on the Physicochemical and Mechanical Properties of Bovine Hydroxyapatite Bone Substitutes

by Abdelmoneim, D., Coates, D.E, Duncan, W.J, Hammer, N., Li, K.C, Porter, G.C, Waddell, J.N
Published 2022

Kidney transplantation from triple-knockout pigs expressing multiple human proteins in cynomolgus macaques

by Coe, T.M, Colvin, R.B, Curtis, M., Hall, K.C, Hirose, T., Kan, Y., Kawai, T., Lassiter, G., Layer, J.V, Ma, D., Markmann, J.F, Matheson, R., Paragas, V.B, Qin, W., Queiroz, L.M, Rickert, C.G, Rosales, I., Sasaki, H., Stiede, K., Westlin, W.F, Yang, L., Youd, M.E
Published 2022

Targeting Cellular DNA Damage Responses in Cancer: An In Vitro-Calibrated Agent-Based Model Simulating Monolayer and Spheroid Treatment Responses to ATR-Inhibiting Drugs

by Chaplain, M.A.J, Hamis, S., Powathil, G.G, Yates, J.
Published 2021

Actin-binding protein Anillin promotes the progression of gastric cancer in vitro and in mice

by Gao, Z., Jia, H., Li, B., Yu, F.
Published 2021

Luteolin enhances the antitumor efficacy of oncolytic vaccinia virus that harbors IL-24 gene in liver cancer cells

by Fang, H., Huang, B., Huang, F., Li, Q., Wang, C., Wang, Y., Xiao, B.
Published 2021