Molecular Landscape and Therapeutic Strategies in Cholangiocarcinoma: An Integrated Translational Approach towards Precision Medicine

by Marco Casadio, Francesca Biancaniello, Diletta Overi, Rosanna Venere, Guido Carpino, Eugenio Gaudio, Domenico Alvaro, Vincenzo Cardinale
Published 2021-05-01

Distinct EpCAM-Positive Stem Cell Niches Are Engaged in Chronic and Neoplastic Liver Diseases

by Samira Safarikia, Guido Carpino, Diletta Overi, Vincenzo Cardinale, Rosanna Venere, Antonio Franchitto, Paolo Onori, Domenico Alvaro, Eugenio Gaudio
Published 2020-09-01

The Charming World of the Extracellular Matrix: A Dynamic and Protective Network of the Intestinal Wall

by Simona Pompili, Giovanni Latella, Eugenio Gaudio, Roberta Sferra, Antonella Vetuschi
Published 2021-04-01

The Role of Autophagy in Liver Epithelial Cells and Its Impact on Systemic Homeostasis

by Luana Tomaipitinca, Sara Mandatori, Romina Mancinelli, Federico Giulitti, Simonetta Petrungaro, Viviana Moresi, Antonio Facchiano, Elio Ziparo, Eugenio Gaudio, Claudia Giampietri
Published 2019-04-01

c-FLIP regulates autophagy by interacting with Beclin-1 and influencing its stability

by Luana Tomaipitinca, Simonetta Petrungaro, Pasquale D’Acunzo, Angelo Facchiano, Amit Dubey, Salvatore Rizza, Federico Giulitti, Eugenio Gaudio, Antonio Filippini, Elio Ziparo, Francesco Cecconi, Claudia Giampietri
Published 2021-07-01

Peribiliary gland damage due to liver transplantation involves peribiliary vascular plexus and vascular endothelial growth factor

by Antonio Franchitto, Diletta Overi, Romina Mancinelli, Anna Paola Mitterhofer, Paolo Muiesan, Francesca Tinti, Ilaria Umbro, Stefan G. Hubscher, Paolo Onori, Eugenio Gaudio, Guido Carpino
Published 2019-05-01

Different iron-handling in inflamed small and large cholangiocytes and in small and large-duct type intrahepatic cholangiocarcinoma

by Romina Mancinelli, Antimo Cutone, Luigi Rosa, Maria Stefania Lepanto, Paolo Onori, Luigi Pannarale, Antonio Franchitto, Eugenio Gaudio, Piera Valenti
Published 2020-10-01

Hepatocyte Injury and Hepatic Stem Cell Niche in the Progression of Non-Alcoholic Steatohepatitis

by Diletta Overi, Guido Carpino, Antonio Franchitto, Paolo Onori, Eugenio Gaudio
Published 2020-03-01

Viral Hepatitis and Iron Dysregulation: Molecular Pathways and the Role of Lactoferrin

by Romina Mancinelli, Luigi Rosa, Antimo Cutone, Maria Stefania Lepanto, Antonio Franchitto, Paolo Onori, Eugenio Gaudio, Piera Valenti
Published 2020-04-01

Contribution of Resident Stem Cells to Liver and Biliary Tree Regeneration in Human Diseases

by Diletta Overi, Guido Carpino, Vincenzo Cardinale, Antonio Franchitto, Samira Safarikia, Paolo Onori, Domenico Alvaro, Eugenio Gaudio
Published 2018-09-01

Stem/Progenitor Cell Niches Involved in Hepatic and Biliary Regeneration

by Guido Carpino, Anastasia Renzi, Antonio Franchitto, Vincenzo Cardinale, Paolo Onori, Lola Reid, Domenico Alvaro, Eugenio Gaudio
Published 2016-01-01

Neuroendocrine Changes in Cholangiocarcinoma Growth

by Keisaku Sato, Heather Francis, Tianhao Zhou, Fanyin Meng, Lindsey Kennedy, Burcin Ekser, Leonardo Baiocchi, Paolo Onori, Romina Mancinelli, Eugenio Gaudio, Antonio Franchitto, Shannon Glaser, Gianfranco Alpini
Published 2020-02-01

Metformin exerts anti-cancerogenic effects and reverses epithelial-to-mesenchymal transition trait in primary human intrahepatic cholangiocarcinoma cells

by Sabina Di Matteo, Lorenzo Nevi, Diletta Overi, Nadine Landolina, Jessica Faccioli, Federico Giulitti, Chiara Napoletano, Andrea Oddi, Augusto M. Marziani, Daniele Costantini, Agostino M. De Rose, Fabio Melandro, Maria C. Bragazzi, Gian Luca Grazi, Pasquale B. Berloco, Felice Giuliante, Giuseppe Donato, Lorenzo Moretta, Guido Carpino, Vincenzo Cardinale, Eugenio Gaudio, Domenico Alvaro
Published 2021-01-01

Overexpression of the Vitronectin V10 Subunit in Patients with Nonalcoholic Steatohepatitis: Implications for Noninvasive Diagnosis of NASH

by Maria Del Ben, Diletta Overi, Licia Polimeni, Guido Carpino, Giancarlo Labbadia, Francesco Baratta, Daniele Pastori, Valeria Noce, Eugenio Gaudio, Francesco Angelico, Carmine Mancone
Published 2018-02-01

Liquid Biopsy in Rare Cancers: Lessons from Hemangiopericytoma

by Chiara Nicolazzo, Luciano Colangelo, Alessandro Corsi, Guido Carpino, Angela Gradilone, Chiara Sonato, Cristina Raimondi, Eugenio Gaudio, Paola Gazzaniga, Walter Gianni
Published 2018-01-01

Cryopreservation protocol for human biliary tree stem/progenitors, hepatic and pancreatic precursors

by Lorenzo Nevi, Vincenzo Cardinale, Guido Carpino, Daniele Costantini, Sabina Di Matteo, Alfredo Cantafora, Fabio Melandro, Roberto Brunelli, Carlo Bastianelli, Camilla Aliberti, Marco Monti, Daniela Bosco, Pasquale Bartolomeo Berloco, Pierluigi Benedetti Panici, Lola Reid, Eugenio Gaudio, Domenico Alvaro
Published 2017-07-01

The Propensity of the Human Liver to Form Large Lipid Droplets Is Associated with PNPLA3 Polymorphism, Reduced INSIG1 and NPC1L1 Expression and Increased Fibrogenetic Capacity

by Flaminia Ferri, Simone Carotti, Guido Carpino, Monica Mischitelli, Alfredo Cantafora, Antonio Molinaro, Maria Eva Argenziano, Simona Parisse, Alessandro Corsi, Mara Riminucci, Quirino Lai, Gianluca Mennini, Gustavo Spadetta, Francesco Pugliese, Massimo Rossi, Sergio Morini, Eugenio Gaudio, Stefano Ginanni Corradini
Published 2021-06-01

The Role of Tissue Macrophage-Mediated Inflammation on NAFLD Pathogenesis and Its Clinical Implications

by Anna Alisi, Guido Carpino, Felipe L. Oliveira, Nadia Panera, Valerio Nobili, Eugenio Gaudio
Published 2017-01-01

Interaction between sphingosine kinase/sphingosine 1 phosphate and transforming growth factor-β/Smads pathways in experimental intestinal fibrosis. An in vivo immunohistochemical s...

by Roberta Sferra, Simona Pompili, Luca Ventura, Caroline Dubuquoy, Silvia Speca, Eugenio Gaudio, Giovanni Latella, Antonella Vetuschi
Published 2018-07-01

Can Nrf2 Modulate the Development of Intestinal Fibrosis and Cancer in Inflammatory Bowel Disease?

by Simona Pompili, Roberta Sferra, Eugenio Gaudio, Angelo Viscido, Giuseppe Frieri, Antonella Vetuschi, Giovanni Latella
Published 2019-08-01