Genome-wide association study and functional validation implicates JADE1 in tauopathy

by Andrews, S.J, Attems, J., Ayalon, G., Beach, T.G, Bhangale, T., Borukov, V.Y, Bowles, K.R, Cairns, N.J, Casella, A., Cherry, J.D, Cobos, I., Cohen, H.T, Corrada, M.M, Cortes, E.P, Crary, J.F, Dangoor, D.K, de Paiva Lopes, K., Dickson, D.W, Farrell, K., Fischer, P., Flanagan, M.E, Franklin, E.E, Frosch, M.P, Frost, B., Fulton-Howard, B., Gandy, S., Gearing, M., Glass, J., Goate, A., Gonzalez, E.M, Graham, R.R, Han, N., Haroutunian, V., Hefti, M.M, Hof, P.R, Humphrey, J., Hunkapiller, J., Hyman, B.T, Iida, M.A, Kapoor, M., Kawas, C.H, Keene, C.D, Kim, S.H, Kofler, J., Kovacs, G.G, Latimer, C.S, Lee, E.B, Lutz, M.I, Mao, Q., Marcora, E., McKee, A.C, McMillan, C.T, Mesulam, M.-M, Metcalf, J., Montine, T.J, Murray, M.E, Nelson, P.T, Novikova, G., Otero-Garcia, M., Perrin, R.J, Pham, T., Poon, W., Purohit, D.P, Raj, T., Renton, A.E, Richardson, T.E, Rissman, R.A, Salehi, B., Sano, M., Schneider, J.A, Shuldberg, S., Sissoko, C.T, Stein, T.D, Tang, W., Teich, A.F, Trojanowski, J.Q, Troncoso, J.C, Udine, E., Vialle, R.A, Vonsattel, J.-P, Walker, J.M, Walsh, H., Weintraub, S., White III, C.L, Whitney, K., Wolk, D.A, Woltjer, R.L, Wong, G., Yu, L.
Published 2022

Systematic Pharmacogenomics Analysis of a Malay Whole Genome: Proof of Concept for Personalized Medicine

by Adam, A., Ahmed, A.Z, Hamzah, A.S, Hatta, F.H.M, Hoh, B.P, Ismail, M.I, Ismet, R.I, Janor, R.M, Joshi, K., Lee, L.S, Pasha, A., Patowary, A., Salleh, M.Z, Scaria, V., Sivasubbu, S., Teh, L.K, Yusoff, K.

Multi-ancestry genome-wide association study of asthma exacerbations

by Ampleford, E.J, Bahmer, T., Bleecker, E., Brinkman, P., Brusselle, G., Burchard, E.G, Canino, G., Celedón, J.C, Chew, F.T, Cloutier, M., Corcuera, P., Cruz, M.J, de Roos, E., Del Pozo, V., Eng, C., Espuela-Ortiz, A., Figueiredo, C., Forno, E., González-Barcala, F.-J, González-Pérez, R., Gorenjak, M., Granell, R., Hansen, G., Hashimoto, S., Hawcutt, D.B, Hawkins, G.A, Hernandez-Pacheco, N., Hernández-Pérez, J.M, Herrera-Luis, E., Jorgensen, A.L, Kabesch, M., Kopp, M.V, Korta-Murua, J., Lethem, R., Lorenzo-Diaz, F., Maitland-van der Zee, A.H, Marsico, A., Martin-Gonzalez, E., Melén, E., Meyers, D., Mukhopadhyay, S., Olaguibel, J.M, Ortega, V.E, Palmer, C.N, Perez-Garcia, J., Pino-Yanes, M., Pirmohamed, M., Plaza, V., Potočnik, U., Poza-Guedes, P., Quirce, S., Rabe, K.F, Rios, R., Rodriguez-Santana, J.R, Sardón, O., Sio, Y.Y, Terzikhan, N., Turner, S., U-BIOPRED Study Group, Vergara, E.E, Vijverberg, S.J, Villar, J., von Mutius, E., Yan, Q.
Published 2022

Untangling the genomics of noise-induced hearing loss and tinnitus: Contributions of Mus musculus and Homo sapiens

by Clifford, R.E, Hertzano, R., Ohlemiller, K.K
Published 2019

Functional characterisation of the amyotrophic lateral sclerosis risk locus GPX3/TNIP1

by Bye, C.R, Cheng, F.-F, Garton, F.C, Giacomotto, J., Gusev, A., Henders, A.K, Henderson, R.D, Kabashi, E., Kiernan, M.C, Mathers, S., McCombe, P.A, McRae, A.F, Nabais, M.F, Needham, M., Ngo, S.T, Ophoff, R., Qi, T., Restuadi, R., Schultz, D., Steyn, F.J, Thompson, M.J, Turner, B.J, van den Berg, L.H, van Rheenen, W., Veldink, J.H, Wallace, L., Wray, N.R, Wu, Y., Zaitlen, N., Ziser, L.
Published 2022

Deep Learning Framework for Complex Disease Risk Prediction Using Genomic Variations

by Alzoubi, H., Alzubi, R., Ramzan, N.
Published 2023

Genome-wide variant-based study of genetic effects with the largest neuroanatomic coverage

by Bao, P., Chen, F., Fang, S., Gao, Y., Jiang, H., Li, H., Li, J., Li, Y., Liang, H., Liu, W., Luo, H.
Published 2021

Genome-wide association studies dissect the genetic architecture of seed shape and size in common bean

by Chiorato, A.F, Gama, H.C, Garcia, A.A.F, Giordani, W., Vieira, M.L.C
Published 2022

The genetic architecture of structural left–right asymmetry of the human brain

by Carrion-Castillo, A., Crivello, F., Fisher, S.E, Francks, C., Joliot, M., Mazoyer, B., Schijven, D., Sha, Z.
Published 2021

qtlXplorer: an online systems genetics browser in the Eucalyptus Genome Integrative Explorer (EucGenIE)

by Christie, N., Delhomme, N., Mähler, N., Mannapperuma, C., Mizrachi, E., Myburg, A.A, Naidoo, S., Ployet, R., Street, N.R, van der Merwe, K.
Published 2021

Whole Genome Sequence Analysis of the Plasma Proteome in Black Adults Provides Novel Insights Into Cardiovascular Disease

by Benson, M.D, Bick, A.G, Bouchard, C., Chen, Z.-Z, Correa, A., Cruz, D.E, Deng, S., Durda, P., Farrell, L., Gao, Y., Gerszten, R.E, Guo, X., Hall, M.E, Ida Chen, Y.-D, Jain, D., Johnson, W.C, Katz, D.H, Liu, Y., Manichaikul, A.W, Natarajan, P., National Heart, Lung, and Blood Institute TOPMed (Trans-Omics for Precision Medicine) Consortium, Ngo, D., Pampana, A., Rich, S.S, Robbins, J.M, Rotter, J.I, Sarzynski, M.A, Schmaier, A.A, Shen, D., Sinha, S., Tahir, U.A, Taylor, K.D, Tracy, R.P, Wang, T.J, Wilson, J.G, Yao, J., Yu, Z.
Published 2022

LDexpress: an online tool for integrating population-specific linkage disequilibrium patterns with tissue-specific expression data

by Lin, S.-H, Machiela, M.J, Thakur, R.
Published 2021

Meta-analysis of genome-wide association studies identifies ancestry-specific associations underlying circulating total tau levels

by Ahmad, S., Beiser, A.S, Bis, J.C, Boerwinkle, E., Bouteloup, V., Chouraki, V., Cupples, L.A, Damotte, V., Debette, S., DeCarli, C.S, DeStefano, A.L, Djoussé, L., Dufouil, C., Fohner, A.E, Fornage, M., Franz, C.E, Ghanbari, M., Ikram, M.A, Kautz, T.F, Kremen, W.S, Lambert, J.-C, Launer, L.J, Logue, M., Longstreth, W.T, Lyons, M.J, Mishra, A., Mosley, T.H, Mukamal, K.J, Pase, M.P, Portilla Fernandez, E.C, Rissman, R.A, Sarnowski, C., Satizabal, C.L, Seshadri, S., Vasan, R.S, Yaqub, A.
Published 2022

Wavelet Screening: a novel approach to analyzing GWAS data

by Denault, W.R.P, Gjessing, H.K, Jacobsson, B., Jugessur, A., Juodakis, J.
Published 2021

gJLS2: an R package for generalized joint location and scale analysis in X-inclusive genome-wide association studies

by Deng, W.Q, Sun, L.
Published 2022

Genome-wide association study identifies SNP markers and putative candidate genes for terpene...

by Külheim, C., Mhoswa, L., Myburg, A.A, Naidoo, S., Slippers, B.
Published 2022

GWAS on multiple traits identifies mitochondrial ACONITASE3 as important for acclimation to submergence stress

by Berkowitz, O., Borevitz, J., Fournier-Level, A., He, C., Jost, R., Kangasjärvi, S., Li, L., Meng, X., Pascual, J., Rahikainen, M., Whelan, J., Yi, C.
Published 2022

A globally diverse reference alignment and panel for imputation of mitochondrial DNA variants

by Andrews, S.J, Easteal, S., for the Alzheimer's Disease Neuroimaging Initiative, Fulton-Howard, B., Goate, A., Jermiin, L.S, McInerney, T.W, Pa, J., Paliwal, D., Patel, H.R, Patterson, C., Swerdlow, R.H
Published 2021

Multidimensional chromatin profiling of zebrafish pancreas to uncover and investigate disease-relevant enhancers

by Acemel, R.D, Bessa, J., Bordeira-Carriço, R., Carneiro, F., Duque, M., Eufrásio, A., Ferreira, F.J, Firbas, P.N, Freitas, T., Galhardo, M., Goméz-Skarmeta, J.L, Marques, J., Ribeiro, D., Teixeira, J., Tena, J.J
Published 2022

Multidimensional chromatin profiling of zebrafish pancreas to uncover and investigate disease-relevant enhancers

by Acemel, R.D, Bessa, J., Bordeira-Carriço, R., Carneiro, F., Duque, M., Eufrásio, A., Ferreira, F.J, Firbas, P.N, Freitas, T., Galhardo, M., Goméz-Skarmeta, J.L, Marques, J., Ribeiro, D., Teixeira, J., Tena, J.J
Published 2022