protein expression Article 84 controlled study 77 human 70 Humans 57 genetics 52 metabolism 51 unclassified drug 49 nonhuman 42 gene expression 41 male 40 upregulation 38 human cell 35 female 34 gene expression regulation 34 Western blotting 31 pathology 31 adult 30 down regulation 30 human tissue 28 real time polymerase chain reaction 28 Animals 27 animal 26 animal experiment 26 Male 25 Female 23 animal cell 23 cell proliferation 23 Gene Expression Regulation, Neoplastic 20 animal model 20