Cis-regulatory variants affect gene expression dynamics in yeast

by Ching-Hua Shih, Justin Fay
Published 2021-08-01

Single-cell RNA analysis identifies pre-migratory neural crest cells expressing markers of differentiated derivatives

by Ezra Lencer, Rytis Prekeris, Kristin Bruk Artinger
Published 2021-08-01

The role of interspecies recombination in the evolution of antibiotic-resistant pneumococci

by Joshua C D'Aeth, Mark PG van der Linden, Lesley McGee, Herminia de Lencastre, Paul Turner, Jae-Hoon Song, Stephanie W Lo, Rebecca A Gladstone, Raquel Sá-Leão, Kwan Soo Ko, William P Hanage, Robert F Breiman, Bernard Beall, Stephen D Bentley, Nicholas J Croucher, The GPS Consortium
Published 2021-07-01

Developing a multivariate prediction model of antibody features associated with protection of malaria-infected pregnant women from placental malaria

by Elizabeth H Aitken, Timon Damelang, Amaya Ortega-Pajares, Agersew Alemu, Wina Hasang, Saber Dini, Holger W Unger, Maria Ome-Kaius, Morten A Nielsen, Ali Salanti, Joe Smith, Stephen Kent, P Mark Hogarth, Bruce D Wines, Julie A Simpson, Amy W Chung, Stephen J Rogerson
Published 2021-06-01

Deep learning detects cardiotoxicity in a high-content screen with induced pluripotent stem cell-derived cardiomyocytes

by Francis Grafton, Jaclyn Ho, Sara Ranjbarvaziri, Farshad Farshidfar, Anastasiia Budan, Stephanie Steltzer, Mahnaz Maddah, Kevin E Loewke, Kristina Green, Snahel Patel, Tim Hoey, Mohammad Ali Mandegar
Published 2021-08-01

A CTP-dependent gating mechanism enables ParB spreading on DNA

by Adam SB Jalal, Ngat T Tran, Clare EM Stevenson, Afroze Chimthanawala, Anjana Badrinarayanan, David M Lawson, Tung BK Le
Published 2021-08-01

Temporal pattern and synergy influence activity of ERK signaling pathways during L-LTP induction

by Nadiatou T Miningou Zobon, Joanna Jędrzejewska-Szmek, Kim T Blackwell
Published 2021-08-01

Endomembrane targeting of human OAS1 p46 augments antiviral activity

by Frank W Soveg, Johannes Schwerk, Nandan S Gokhale, Karen Cerosaletti, Julian R Smith, Erola Pairo-Castineira, Alison M Kell, Adriana Forero, Shivam A Zaver, Katharina Esser-Nobis, Justin A Roby, Tien-Ying Hsiang, Snehal Ozarkar, Jonathan M Clingan, Eileen T McAnarney, Amy EL Stone, Uma Malhotra, Cate Speake, Joseph Perez, Chiraag Balu, Eric J Allenspach, Jennifer L Hyde, Vineet D Menachery, Saumendra N Sarkar, Joshua J Woodward, Daniel B Stetson, John Kenneth Baillie, Jane H Buckner, Michael Gale Jr, Ram Savan
Published 2021-08-01

Resonating neurons stabilize heterogeneous grid-cell networks

by Divyansh Mittal, Rishikesh Narayanan
Published 2021-07-01

CTP and parS coordinate ParB partition complex dynamics and ParA-ATPase activation for ParABS-mediated DNA partitioning

by James A Taylor, Yeonee Seol, Jagat Budhathoki, Keir C Neuman, Kiyoshi Mizuuchi
Published 2021-07-01

TGFβ signalling is required to maintain pluripotency of human naïve pluripotent stem cells

by Anna Osnato, Stephanie Brown, Christel Krueger, Simon Andrews, Amanda J Collier, Shota Nakanoh, Mariana Quiroga Londoño, Brandon T Wesley, Daniele Muraro, A Sophie Brumm, Kathy K Niakan, Ludovic Vallier, Daniel Ortmann, Peter J Rugg-Gunn
Published 2021-08-01

Augmin deficiency in neural stem cells causes p53-dependent apoptosis and aborts brain development

by Ricardo Viais, Marcos Fariña-Mosquera, Marina Villamor-Payà, Sadanori Watanabe, Lluís Palenzuela, Cristina Lacasa, Jens Lüders
Published 2021-08-01

Sterically confined rearrangements of SARS-CoV-2 Spike protein control cell invasion

by Esteban Dodero-Rojas, Jose N Onuchic, Paul Charles Whitford
Published 2021-08-01

Combinations of maternal-specific repressive epigenetic marks in the endosperm control seed dormancy

by Hikaru Sato, Juan Santos-González, Claudia Köhler
Published 2021-08-01

Glypicans define unique roles for the Hedgehog co-receptors boi and ihog in cytoneme-mediated gradient formation

by Eléanor Simon, Carlos Jiménez-Jiménez, Irene Seijo-Barandiarán, Gustavo Aguilar, David Sánchez-Hernández, Adrián Aguirre-Tamaral, Laura González-Méndez, Pedro Ripoll, Isabel Guerrero
Published 2021-08-01

KLF10 integrates circadian timing and sugar signaling to coordinate hepatic metabolism

by Anthony A Ruberto, Aline Gréchez-Cassiau, Sophie Guérin, Luc Martin, Johana S Revel, Mohamed Mehiri, Malayannan Subramaniam, Franck Delaunay, Michèle Teboul
Published 2021-08-01

What can we learn from honey bees?

by Julia A Schwartzman
Published 2021-08-01

Patterns of within-host genetic diversity in SARS-CoV-2

by Gerry Tonkin-Hill, Inigo Martincorena, Roberto Amato, Andrew RJ Lawson, Moritz Gerstung, Ian Johnston, David K Jackson, Naomi Park, Stefanie V Lensing, Michael A Quail, Sónia Gonçalves, Cristina Ariani, Michael Spencer Chapman, William L Hamilton, Luke W Meredith, Grant Hall, Aminu S Jahun, Yasmin Chaudhry, Myra Hosmillo, Malte L Pinckert, Iliana Georgana, Anna Yakovleva, Laura G Caller, Sarah L Caddy, Theresa Feltwell, Fahad A Khokhar, Charlotte J Houldcroft, Martin D Curran, Surendra Parmar, The COVID-19 Genomics UK (COG-UK) Consortium, Alex Alderton, Rachel Nelson, Ewan M Harrison, John Sillitoe, Stephen D Bentley, Jeffrey C Barrett, M Estee Torok, Ian G Goodfellow, Cordelia Langford, Dominic Kwiatkowski, Wellcome Sanger Institute COVID-19 Surveillance Team
Published 2021-08-01

Niche partitioning facilitates coexistence of closely related honey bee gut bacteria

by Silvia Brochet, Andrew Quinn, Ruben AT Mars, Nicolas Neuschwander, Uwe Sauer, Philipp Engel
Published 2021-07-01

Studying evolution of the primary body axis in vivo and in vitro

by Kerim Anlas, Vikas Trivedi
Published 2021-08-01