metabolism 491 human 312 genetics 307 Humans 288 Article 213 Animals 198 animal 195 controlled study 182 gene expression regulation 159 male 129 female 128 mouse 126 nonhuman 124 Mice 108 Female 104 pathology 104 unclassified drug 101 gene expression 97 Male 96 adult 89 protein expression 82 cell proliferation 80 upregulation 79 signal transduction 77 human cell 75 down regulation 72 Cell Proliferation 69 Gene Expression Regulation, Neoplastic 66 Cell Line, Tumor 63 animal experiment 63